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    Gtf2ird1 general transcription factor II I repeat domain-containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 57080, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gtf2ird1provided by MGI
    Official Full Name
    general transcription factor II I repeat domain-containing 1provided by MGI
    Primary source
    MGI:MGI:1861942
    See related
    Ensembl:ENSMUSG00000023079 AllianceGenome:MGI:1861942
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BEN; GTF3; ESTM9; Cream1; Gtf2il; MusTRD1; WBSCR11; 1700012P16Rik; Tg(Alb1-Myc)166.8Sst
    Summary
    Enables DNA-binding transcription factor activity. Acts upstream of or within transition between slow and fast fiber. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; eye; and genitourinary system. Used to study Williams-Beuren syndrome and hepatocellular carcinoma. Orthologous to human GTF2IRD1 (GTF2I repeat domain containing 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 16.4), CNS E11.5 (RPKM 13.0) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Gtf2ird1 in Genome Data Viewer
    Location:
    5 G2; 5 74.55 cM
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (134386515..134485628, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (134357661..134456867, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46925 Neighboring gene predicted gene 7033 Neighboring gene CapStarr-seq enhancer MGSCv37_chr5:134920313-134920568 Neighboring gene STARR-seq mESC enhancer starr_14545 Neighboring gene ribosomal protein S28 pseudogene Neighboring gene STARR-seq mESC enhancer starr_14546 Neighboring gene CAP-GLY domain containing linker protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E11305

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Regulation of alternative splicing of Gtf2ird1 and its impact on slow muscle promoter activity. Tay ES, et al. Biochem J, 2003 Sep 1. PMID 12780350, Free PMC Article
    2. In vivo MRS assessment of altered fatty acyl unsaturation in liver tumor formation of a TGF alpha/c-myc transgenic mouse model. Griffitts J, et al. J Lipid Res, 2009 Apr. PMID 19065002, Free PMC Article
    3. Nonrandom cytogenetic alterations in hepatocellular carcinoma from transgenic mice overexpressing c-Myc and transforming growth factor-alpha in the liver. Sargent LM, et al. Am J Pathol, 1999 Apr. PMID 10233843, Free PMC Article
    4. Enhanced prefrontal serotonin 5-HT(1A) currents in a mouse model of Williams-Beuren syndrome with low innate anxiety. Proulx E, et al. J Neurodev Disord, 2010 Jun. PMID 20585377, Free PMC Article
    5. Reduced fear and aggression and altered serotonin metabolism in Gtf2ird1-targeted mice. Young EJ, et al. Genes Brain Behav, 2008 Mar. PMID 17680805, Free PMC Article

    See all (96) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences.
      Title: Functions of Gtf2i and Gtf2ird1 in the developing brain: transcription, DNA binding and long-term behavioral consequences.
    2. Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models
      Title: Gtf2i and Gtf2ird1 mutation do not account for the full phenotypic effect of the Williams syndrome critical region in mouse models.
    3. GTF2IRD1 represses the transcription of transforming growth factor beta-dependent pro-fibrosis genes by recruiting PRDM16 and EHMT1 onto their promoter/enhancer regions.
      Title: Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis.
    4. The mis-regulation of genes downstream of GTF2IRD1, including TbetaR2 and BMPR1b, also individually promoted mammary cancer development, and silencing of TbetaR2 suppressed GTF2IRD1-driven tumor promotion.
      Title: An In Vivo Gain-of-Function Screen Identifies the Williams-Beuren Syndrome Gene GTF2IRD1 as a Mammary Tumor Promoter.
    5. the absence of GTF2IRD1 is associated with increased expression of genes involved in cellular proliferation, including growth factors consistent with the observed phenotype of extreme thickening of the epidermis.
      Title: RNA-Seq analysis of Gtf2ird1 knockout epidermal tissue provides potential insights into molecular mechanisms underpinning Williams-Beuren syndrome.
    6. Gtf2ird1 is essential for Mkx transcription, while also linking mechanical forces to Mkx-mediated tendon homeostasis and regeneration.
      Title: Gtf2ird1-Dependent Mohawk Expression Regulates Mechanosensing Properties of the Tendon.
    7. Gtf2ird1 is expressed in a number of cell types within the cochlea. Gtf2ird1 null mice showed higher auditory thresholds.
      Title: The role of GTF2IRD1 in the auditory pathology of Williams-Beuren Syndrome.
    8. findings suggest an important role for GTF2IRD1 in regulating the level and topology of rod and cone gene expression, and in maintaining normal retinal function.
      Title: The transcription factor GTF2IRD1 regulates the topology and function of photoreceptors by modulating photoreceptor gene expression across the retina.
    9. GTF2IRD2 has evolved as a regulator of GTF2IRD1 and TFII-I; inhibiting their function by direct interaction and sequestration into inactive nuclear zones.
      Title: GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members.
    10. This study presented that role for GTF2IRD1 in the motoric and anxiety-related abnormalities seen in Williams-Beuren syndrome, and suggests basal ganglia and potentially cerebellar abnormalities in Gtf2ird1 mice.
      Title: Anxious, hypoactive phenotype combined with motor deficits in Gtf2ird1 null mouse model relevant to Williams syndrome.
    Submit: New GeneRIF Correction See all GeneRIFs (22)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC102438

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within embryo development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within transition between slow and fast fiber IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    general transcription factor II-I repeat domain-containing protein 1
    Names
    Alb/c-myc line 166.8
    GTF2I repeat domain-containing 1
    GTF2I repeat domain-containing protein 1
    Williams-Beuren syndrome chromosome region 11
    binding factor for early enhancer
    c-myc line 166.8
    general transcription factor 3
    muscle TFII-I repeat domain-containing protein 1
    transcription factor GTF3 alpha 2
    transcription factor GTF3 gamma 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081462.2 → NP_001074931.1  general transcription factor II-I repeat domain-containing protein 1 isoform b

      See identical proteins and their annotated locations for NP_001074931.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 3' coding region and the 3' UTR, as compared to variant 1. The encoded isoform (b) has a longer and distinct C-terminus, as compared to isoform a.
      Source sequence(s)
      AC167419, AF257475, AI413504, CJ178886
      Consensus CDS
      CCDS39307.1
      UniProtKB/Swiss-Prot
      Q547E0, Q80WJ8, Q80WJ9, Q80WK0, Q80WK1, Q8R4X5, Q8R4X6, Q8R4X7, Q8R4X8, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7, Q9JI57
      UniProtKB/TrEMBL
      Q8BP10
      Related
      ENSMUSP00000098217.4, ENSMUST00000100652.10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    2. NM_001081463.2 → NP_001074932.1  general transcription factor II-I repeat domain-containing protein 1 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 3' coding region and the 3' UTR, as compared to variant 1. The encoded isoform (c) lacks an internal segment and has a longer and distinct C-terminus, as compared to isoform a.
      Source sequence(s)
      AC167419, AF343350, AI413504, AK078488, CJ178886
      Consensus CDS
      CCDS39306.1
      UniProtKB/TrEMBL
      Q8BP10
      Related
      ENSMUSP00000098215.4, ENSMUST00000100650.10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    3. NM_001081464.2 → NP_001074933.1  general transcription factor II-I repeat domain-containing protein 1 isoform d

      See identical proteins and their annotated locations for NP_001074933.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an in-frame exon in the coding region, as compared to variant 1. The encoded isoform (d) lacks an internal segment, as compared to isoform a.
      Source sequence(s)
      BC050822, CJ178886
      Consensus CDS
      CCDS39304.1
      UniProtKB/TrEMBL
      Q5XJY7, Q6PD35
      Related
      ENSMUSP00000129392.3, ENSMUST00000171794.9
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    4. NM_001081465.1 → NP_001074934.1  general transcription factor II-I repeat domain-containing protein 1 isoform d

      See identical proteins and their annotated locations for NP_001074934.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) differs in the 5' UTR and lacks an in-frame coding exon, as compared to variant 1. The encoded isoform (d) lacks an internal segment, as compared to isoform a.
      Source sequence(s)
      AK078488, BC050822, BC083150, CJ048288
      Consensus CDS
      CCDS39304.1
      UniProtKB/TrEMBL
      Q5XJY7, Q6PD35
      Related
      ENSMUSP00000106875.2, ENSMUST00000111244.5
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    5. NM_001081466.2 → NP_001074935.1  general transcription factor II-I repeat domain-containing protein 1 isoform e

      See identical proteins and their annotated locations for NP_001074935.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks two in-frame exons in the coding region, as compared to variant 1. The encoded isoform (e) lacks two segments, as compared to isoform a.
      Source sequence(s)
      AF343349, BC050822, CJ178886
      Consensus CDS
      CCDS39302.1
      UniProtKB/TrEMBL
      Q5XJY7
      Related
      ENSMUSP00000106876.3, ENSMUST00000111245.9
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    6. NM_001081467.2 → NP_001074936.1  general transcription factor II-I repeat domain-containing protein 1 isoform f

      See identical proteins and their annotated locations for NP_001074936.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) differs in the 3' coding region and the 3' UTR, as compared to variant 1. The encoded isoform (f) lacks an internal segment and has a longer and distinct C-terminus, as compared to isoform a.
      Source sequence(s)
      AC167419, AF257475, AI413504, BC050822, CJ178886
      Consensus CDS
      CCDS51657.1
      UniProtKB/TrEMBL
      Q8BP10
      Related
      ENSMUSP00000073752.6, ENSMUST00000074114.12
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    7. NM_001081468.2 → NP_001074937.1  general transcription factor II-I repeat domain-containing protein 1 isoform g

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) lacks three exons in the 3' coding region but maintains the reading frame, as compared to variant 1. The encoded isoform (g) lacks an internal segment, as compared to isoform a.
      Source sequence(s)
      BC050822, CJ178886
      Consensus CDS
      CCDS39303.1
      UniProtKB/TrEMBL
      A0A0J9YTX7
      Related
      ENSMUSP00000098219.4, ENSMUST00000100654.10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    8. NM_001081469.2 → NP_001074938.1  general transcription factor II-I repeat domain-containing protein 1 isoform h

      See identical proteins and their annotated locations for NP_001074938.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) lacks three exons in the 3' coding region but maintains the reading frame, as compared to variant 1. The encoded isoform (h) lacks an internal segment, as compared to isoform a.
      Source sequence(s)
      AF257475, BC050822, CJ178886
      Consensus CDS
      CCDS80420.1
      UniProtKB/TrEMBL
      A0A0J9YTX7
      Related
      ENSMUSP00000143848.2, ENSMUST00000200944.4
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    9. NM_001081470.2 → NP_001074939.1  general transcription factor II-I repeat domain-containing protein 1 isoform i

      See identical proteins and their annotated locations for NP_001074939.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (10) lacks four exons in the 3' coding region but maintains the reading frame, as compared to variant 1. The encoded isoform (i) lacks two internal segments, as compared to isoform a.
      Source sequence(s)
      BC050822, CJ178886
      UniProtKB/TrEMBL
      A0A0J9YTX7
      Related
      ENSMUSP00000143897.2, ENSMUST00000202280.4
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    10. NM_001244936.1 → NP_001231865.1  general transcription factor II-I repeat domain-containing protein 1 isoform j

      Status: VALIDATED

      Description
      Transcript Variant: This variant (11) differs in the 3' coding region and the 3' UTR, as compared to variant 1. The encoded isoform (j) lacks two internal segments and has a longer and distinct C-terminus, as compared to isoform a.
      Source sequence(s)
      AC167419, AF257475, AI413504, BC050822, CJ178886
      UniProtKB/TrEMBL
      A0A0J9YTX7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    11. NM_001347488.1 → NP_001334417.1  general transcription factor II-I repeat domain-containing protein 1 isoform k

      Status: VALIDATED

      Description
      Transcript Variant: This variant (12) lacks two in-frame exons and differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (k) lacks two alternate internal segments and has a distinct C-terminus compared to isoform a.
      Source sequence(s)
      AC167419
      Consensus CDS
      CCDS84967.1
      UniProtKB/TrEMBL
      Q8BP10
      Related
      ENSMUSP00000143809.2, ENSMUST00000202554.4
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 639
      GTF2I; GTF2I-like repeat

    12. NM_020331.3 → NP_065064.2  general transcription factor II-I repeat domain-containing protein 1 isoform a

      See identical proteins and their annotated locations for NP_065064.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the full-length transcript containing all exons of the gene. Variant 1 encodes isoform a.
      Source sequence(s)
      AF343348, BC050822, CJ178886
      Consensus CDS
      CCDS39305.1
      UniProtKB/TrEMBL
      Q5XJY7
      Related
      ENSMUSP00000072904.6, ENSMUST00000073161.12
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      134386515..134485628 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017321047.3 → XP_017176536.1  general transcription factor II-I repeat domain-containing protein 1 isoform X28

      UniProtKB/TrEMBL
      A0A0J9YTX7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    2. XM_017321046.3 → XP_017176535.1  general transcription factor II-I repeat domain-containing protein 1 isoform X27

      UniProtKB/TrEMBL
      A0A0J9YTX7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    3. XM_017321044.3 → XP_017176533.1  general transcription factor II-I repeat domain-containing protein 1 isoform X24

      UniProtKB/TrEMBL
      A0A0J9YTX7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    4. XM_017321045.3 → XP_017176534.1  general transcription factor II-I repeat domain-containing protein 1 isoform X25

      UniProtKB/TrEMBL
      A0A0J9YTX7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    5. XM_017321042.3 → XP_017176531.1  general transcription factor II-I repeat domain-containing protein 1 isoform X21

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    6. XM_036165372.1 → XP_036021265.1  general transcription factor II-I repeat domain-containing protein 1 isoform X14

      UniProtKB/TrEMBL
      Q5XJY7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 639
      GTF2I; GTF2I-like repeat

    7. XM_006504462.4 → XP_006504525.1  general transcription factor II-I repeat domain-containing protein 1 isoform X8

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    8. XM_030254729.2 → XP_030110589.1  general transcription factor II-I repeat domain-containing protein 1 isoform X12

      UniProtKB/TrEMBL
      Q5XJY7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    9. XM_017321043.3 → XP_017176532.1  general transcription factor II-I repeat domain-containing protein 1 isoform X22

      UniProtKB/TrEMBL
      A0A0J9YTX7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    10. XM_017321040.3 → XP_017176529.1  general transcription factor II-I repeat domain-containing protein 1 isoform X17

      UniProtKB/TrEMBL
      A0A0J9YTX7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    11. XM_036165370.1 → XP_036021263.1  general transcription factor II-I repeat domain-containing protein 1 isoform X11

      UniProtKB/TrEMBL
      Q5XJY7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 639
      GTF2I; GTF2I-like repeat

    12. XM_011240895.3 → XP_011239197.1  general transcription factor II-I repeat domain-containing protein 1 isoform X9

      UniProtKB/TrEMBL
      Q5XJY7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    13. XM_011240891.3 → XP_011239193.1  general transcription factor II-I repeat domain-containing protein 1 isoform X3

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    14. XM_017321041.3 → XP_017176530.1  general transcription factor II-I repeat domain-containing protein 1 isoform X19

      UniProtKB/TrEMBL
      A0A0J9YTX7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    15. XM_011240894.3 → XP_011239196.1  general transcription factor II-I repeat domain-containing protein 1 isoform X7

      UniProtKB/TrEMBL
      Q5XJY7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    16. XM_011240890.3 → XP_011239192.1  general transcription factor II-I repeat domain-containing protein 1 isoform X2

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    17. XM_011240897.3 → XP_011239199.1  general transcription factor II-I repeat domain-containing protein 1 isoform X18

      UniProtKB/TrEMBL
      A0A0J9YTX7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    18. XM_011240896.3 → XP_011239198.1  general transcription factor II-I repeat domain-containing protein 1 isoform X16

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    19. XM_011240893.3 → XP_011239195.1  general transcription factor II-I repeat domain-containing protein 1 isoform X6

      UniProtKB/TrEMBL
      Q5XJY7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    20. XM_011240892.3 → XP_011239194.1  general transcription factor II-I repeat domain-containing protein 1 isoform X4

      UniProtKB/TrEMBL
      Q5XJY7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    21. XM_011240885.3 → XP_011239187.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011239187.1

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    22. XM_030254732.1 → XP_030110592.1  general transcription factor II-I repeat domain-containing protein 1 isoform X26

      UniProtKB/TrEMBL
      Q5XJY7
      Conserved Domains (1) summary
      pfam02946
      Location:422 → 494
      GTF2I; GTF2I-like repeat

    23. XM_011240900.2 → XP_011239202.1  general transcription factor II-I repeat domain-containing protein 1 isoform X29

      Conserved Domains (1) summary
      pfam02946
      Location:349 → 421
      GTF2I; GTF2I-like repeat

    24. XM_030254731.1 → XP_030110591.1  general transcription factor II-I repeat domain-containing protein 1 isoform X23

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:422 → 494
      GTF2I; GTF2I-like repeat

    25. XM_030254733.1 → XP_030110593.1  general transcription factor II-I repeat domain-containing protein 1 isoform X30

      Conserved Domains (1) summary
      pfam02946
      Location:270 → 342
      GTF2I; GTF2I-like repeat

    26. XM_036165377.1 → XP_036021270.1  general transcription factor II-I repeat domain-containing protein 1 isoform X32

      Conserved Domains (1) summary
      pfam02946
      Location:93 → 167
      GTF2I; GTF2I-like repeat

    27. XM_011240886.4 → XP_011239188.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011239188.1

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    28. XM_036165371.1 → XP_036021264.1  general transcription factor II-I repeat domain-containing protein 1 isoform X13

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 639
      GTF2I; GTF2I-like repeat

    29. XM_036165378.1 → XP_036021271.1  general transcription factor II-I repeat domain-containing protein 1 isoform X33

      Conserved Domains (1) summary
      pfam02946
      Location:93 → 167
      GTF2I; GTF2I-like repeat

    30. XM_030254730.2 → XP_030110590.1  general transcription factor II-I repeat domain-containing protein 1 isoform X13

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 639
      GTF2I; GTF2I-like repeat

    31. XM_017321039.3 → XP_017176528.1  general transcription factor II-I repeat domain-containing protein 1 isoform X10

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    32. XM_017321038.2 → XP_017176527.1  general transcription factor II-I repeat domain-containing protein 1 isoform X5

      UniProtKB/Swiss-Prot
      Q547E0, Q80WJ8, Q80WJ9, Q80WK0, Q80WK1, Q8R4X5, Q8R4X6, Q8R4X7, Q8R4X8, Q8VHD5, Q8VI58, Q9EQE7, Q9ESZ6, Q9ESZ7, Q9JI57
      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    33. XM_011240889.2 → XP_011239191.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011239191.1

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    34. XM_011240901.2 → XP_011239203.1  general transcription factor II-I repeat domain-containing protein 1 isoform X30

      Conserved Domains (1) summary
      pfam02946
      Location:270 → 342
      GTF2I; GTF2I-like repeat

    35. XM_011240888.4 → XP_011239190.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011239190.1

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    36. XM_011240887.2 → XP_011239189.1  general transcription factor II-I repeat domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011239189.1

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 637
      GTF2I; GTF2I-like repeat

    37. XM_011240898.2 → XP_011239200.1  general transcription factor II-I repeat domain-containing protein 1 isoform X20

      UniProtKB/TrEMBL
      Q8BP10
      Conserved Domains (1) summary
      pfam02946
      Location:422 → 494
      GTF2I; GTF2I-like repeat

    38. XM_036165376.1 → XP_036021269.1  general transcription factor II-I repeat domain-containing protein 1 isoform X31

      Conserved Domains (1) summary
      pfam02946
      Location:93 → 167
      GTF2I; GTF2I-like repeat

    39. XM_036165373.1 → XP_036021266.1  general transcription factor II-I repeat domain-containing protein 1 isoform X15

      UniProtKB/TrEMBL
      Q5XJY7
      Conserved Domains (1) summary
      pfam02946
      Location:565 → 639
      GTF2I; GTF2I-like repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9JI57.2 GenPept UniProtKB/Swiss-Prot:Q9JI57

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