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    Exoc6 exocyst complex component 6 [ Mus musculus (house mouse) ]

    Gene ID: 107371, updated on 9-Dec-2024

    Summary

    Official Symbol
    Exoc6provided by MGI
    Official Full Name
    exocyst complex component 6provided by MGI
    Primary source
    MGI:MGI:1351611
    See related
    Ensembl:ENSMUSG00000053799 AllianceGenome:MGI:1351611
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    hbd; Sec15; msec15; Sec15l1; C430002C19; 4833405E05Rik
    Summary
    Acts upstream of or within erythrocyte differentiation. Predicted to be located in plasma membrane. Predicted to be part of exocyst. Is expressed in central nervous system; dorsal root ganglion; foregut; genitourinary system; and liver lobe. Orthologous to human EXOC6 (exocyst complex component 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 12.6), liver E14 (RPKM 11.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Exoc6 in Genome Data Viewer
    Location:
    19 C2; 19 32.32 cM
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (37525181..37672499)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (37536763..37684052)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700122C19 gene Neighboring gene predicted gene, 32294 Neighboring gene predicted gene, 41842 Neighboring gene STARR-seq mESC enhancer starr_46060 Neighboring gene STARR-seq mESC enhancer starr_46061 Neighboring gene STARR-seq mESC enhancer starr_46062 Neighboring gene predicted gene, 32342 Neighboring gene cytochrome P450, family 26, subfamily c, polypeptide 1 Neighboring gene cytochrome P450, family 26, subfamily a, polypeptide 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    hemoglobin deficient
    GeneReviews: Not available

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Spontaneous (1)  1 citation
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Golgi to plasma membrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within erythrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in membrane fission NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in mitotic cytokinesis NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in vesicle docking involved in exocytosis NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in vesicle tethering involved in exocytosis NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Flemming body IEA
    Inferred from Electronic Annotation
    more info
     
    part_of exocyst IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of exocyst NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in growth cone IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinuclear region of cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    exocyst complex component 6
    Names
    SEC15 homolog
    SEC15-like 1
    SEC15-like protein 1
    exocyst complex component Sec15A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175353.2NP_780562.2  exocyst complex component 6

      See identical proteins and their annotated locations for NP_780562.2

      Status: VALIDATED

      Source sequence(s)
      AC110212, AK076455, AK082881, BY100185, CD806857
      Consensus CDS
      CCDS29779.1
      UniProtKB/TrEMBL
      A0A5F8MPW8, Q3U9D6
      Related
      ENSMUSP00000064332.7, ENSMUST00000066439.8
      Conserved Domains (1) summary
      pfam04091
      Location:456762
      Sec15; Exocyst complex subunit Sec15-like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      37525181..37672499
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017318044.2XP_017173533.1  exocyst complex component 6 isoform X1

      UniProtKB/TrEMBL
      A0A5F8MP92, A0A5F8MPW8
      Related
      ENSMUSP00000158866.2, ENSMUST00000238954.2
      Conserved Domains (1) summary
      pfam04091
      Location:463769
      Sec15; Exocyst complex subunit Sec15-like