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    UNC13B unc-13 homolog B [ Rhinopithecus roxellana (golden snub-nosed monkey) ]

    Gene ID: 104680034, updated on 12-Mar-2024

    Summary

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    Gene symbol
    UNC13B
    Gene description
    unc-13 homolog B
    See related
    Ensembl:ENSRROG00000032184
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rhinopithecus roxellana
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus
    Orthologs
    human mouse all
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    Genomic context

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    See UNC13B in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    44
    Annotation release Status Assembly Chr Location
    101 current ASM756505v1 (GCF_007565055.1) 16 NC_044564.1 (23558674..23788564, complement)
    100 previous assembly Rrox_v1 (GCF_000769185.1) Unplaced Scaffold NW_010827607.1 (1627920..1857223)

    Chromosome 16 - NC_044564.1Genomic Context describing neighboring genes Neighboring gene ciliary microtubule inner protein 2B Neighboring gene RUN and SH3 domain containing 2 Neighboring gene phospholipid-transporting ATPase FetA-like Neighboring gene 60S ribosomal protein L19 Neighboring gene atos homolog B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables diacylglycerol binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables syntaxin-1 binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in dense core granule priming IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in neuromuscular junction development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in presynaptic dense core vesicle exocytosis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic transmission, glutamatergic IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle docking IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle maturation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in synaptic vesicle priming IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuromuscular junction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynaptic active zone cytoplasmic component IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in presynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in synaptic vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in terminal bouton IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    protein unc-13 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Rhinopithecus roxellana Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM756505v1 Primary Assembly

    Genomic

    1. NC_044564.1 Reference ASM756505v1 Primary Assembly

      Range
      23558674..23788564 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_010385830.2 → XP_010384132.1  protein unc-13 homolog B isoform X3

      UniProtKB/TrEMBL
      A0A2K6PHT5
      Related
      ENSRROP00000016095.1
      Conserved Domains (6) summary
      cd04027
      Location:600 → 726
      C2B_Munc13; C2 domain second repeat in Munc13 (mammalian uncoordinated) proteins
      cd08394
      Location:1 → 127
      C2A_Munc13; C2 domain first repeat in Munc13 (mammalian uncoordinated) proteins
      cd08395
      Location:1439 → 1558
      C2C_Munc13; C2 domain third repeat in Munc13 (mammalian uncoordinated) proteins
      cd00029
      Location:478 → 527
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      pfam06292
      Location:918 → 1020
      DUF1041; Domain of Unknown Function (DUF1041)
      pfam10540
      Location:1265 → 1401
      Membr_traf_MHD; Munc13 (mammalian uncoordinated) homology domain

    2. XM_030920050.1 → XP_030775910.1  protein unc-13 homolog B isoform X1

      UniProtKB/TrEMBL
      A0A2K6PI20
      Conserved Domains (6) summary
      cd04027
      Location:3348 → 3474
      C2B_Munc13; C2 domain second repeat in Munc13 (mammalian uncoordinated) proteins
      cd08394
      Location:1 → 127
      C2A_Munc13; C2 domain first repeat in Munc13 (mammalian uncoordinated) proteins
      cd08395
      Location:4187 → 4306
      C2C_Munc13; C2 domain third repeat in Munc13 (mammalian uncoordinated) proteins
      cd00029
      Location:3226 → 3275
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      pfam06292
      Location:3666 → 3768
      DUF1041; Domain of Unknown Function (DUF1041)
      pfam10540
      Location:4013 → 4149
      Membr_traf_MHD; Munc13 (mammalian uncoordinated) homology domain

    3. XM_030920052.1 → XP_030775912.1  protein unc-13 homolog B isoform X4

      UniProtKB/TrEMBL
      A0A2K6PHT5
      Conserved Domains (6) summary
      cd04027
      Location:600 → 726
      C2B_Munc13; C2 domain second repeat in Munc13 (mammalian uncoordinated) proteins
      cd08394
      Location:1 → 127
      C2A_Munc13; C2 domain first repeat in Munc13 (mammalian uncoordinated) proteins
      cd08395
      Location:1438 → 1557
      C2C_Munc13; C2 domain third repeat in Munc13 (mammalian uncoordinated) proteins
      cd00029
      Location:478 → 527
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      pfam06292
      Location:918 → 1019
      DUF1041; Domain of Unknown Function (DUF1041)
      pfam10540
      Location:1264 → 1400
      Membr_traf_MHD; Munc13 (mammalian uncoordinated) homology domain

    4. XM_030920053.1 → XP_030775913.1  protein unc-13 homolog B isoform X5

      UniProtKB/TrEMBL
      A0A2K6PHU0
      Conserved Domains (5) summary
      cd04027
      Location:185 → 311
      C2B_Munc13; C2 domain second repeat in Munc13 (mammalian uncoordinated) proteins
      cd08395
      Location:1024 → 1143
      C2C_Munc13; C2 domain third repeat in Munc13 (mammalian uncoordinated) proteins
      cd00029
      Location:63 → 112
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      pfam06292
      Location:503 → 605
      DUF1041; Domain of Unknown Function (DUF1041)
      pfam10540
      Location:850 → 986
      Membr_traf_MHD; Munc13 (mammalian uncoordinated) homology domain

    5. XM_030920051.1 → XP_030775911.1  protein unc-13 homolog B isoform X2

      UniProtKB/TrEMBL
      A0A2K6PHT7
      Conserved Domains (5) summary
      cd04027
      Location:980 → 1106
      C2B_Munc13; C2 domain second repeat in Munc13 (mammalian uncoordinated) proteins
      cd08395
      Location:1838 → 1957
      C2C_Munc13; C2 domain third repeat in Munc13 (mammalian uncoordinated) proteins
      cd00029
      Location:858 → 907
      C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
      pfam06292
      Location:1298 → 1400
      DUF1041; Domain of Unknown Function (DUF1041)
      pfam10540
      Location:1645 → 1781
      Membr_traf_MHD; Munc13 (mammalian uncoordinated) homology domain
    Nucleotide Protein
    Heading Accession and Version

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