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    mapkk4 mitogen-activated protein kinase kinase [ Ciona intestinalis (vase tunicate) ]

    Gene ID: 778672, updated on 21-Dec-2023

    Summary

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    Gene symbol
    mapkk4
    Gene description
    mitogen-activated protein kinase kinase
    See related
    Ensembl:ENSCING00000007349
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Ciona intestinalis
    Lineage
    Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Phlebobranchia; Cionidae; Ciona
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    Genomic context

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    See mapkk4 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    104 current KH (GCF_000224145.3) 8 NC_020173.2 (4234277..4238435, complement)

    Chromosome 8 - NC_020173.2Genomic Context describing neighboring genes Neighboring gene chromodomain-helicase-DNA-binding protein 4 Neighboring gene uncharacterized LOC104265910 Neighboring gene uncharacterized LOC100187352 Neighboring gene uncharacterized LOC113474449 Neighboring gene uncharacterized LOC113474441 Neighboring gene golgin subfamily A member 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_020173.2 Chromosome 8 Reference KH Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gene expression profiles of transcription factors and signaling molecules in the ascidian embryo: towards a comprehensive understanding of gene networks. Imai KS, et al. Development, 2004 Aug. PMID 15269171
    2. Genomewide surveys of developmentally relevant genes in Ciona intestinalis. Satou Y, et al. Dev Genes Evol, 2003 Jun. PMID 12736827
    3. A cDNA resource from the basal chordate Ciona intestinalis. Satou Y, et al. Genesis, 2002 Aug. PMID 12203911
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables JUN kinase kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in MAPK cascade IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    mitogen-activated protein kinase kinase

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001078290.1 → NP_001071758.1  mitogen-activated protein kinase kinase

      See identical proteins and their annotated locations for NP_001071758.1

      Status: PROVISIONAL

      Source sequence(s)
      AB210541
      UniProtKB/TrEMBL
      A0A1W2VRU5, F6XXW0, Q4H381
      Related
      ENSCINP00000015099, ENSCINT00000015099
      Conserved Domains (2) summary
      smart00220
      Location:170 → 436
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd06616
      Location:162 → 454
      PKc_MKK4; Catalytic domain of the dual-specificity Protein Kinase, Mitogen-activated protein Kinase Kinase 4

    RefSeqs of Annotated Genomes: Ciona intestinalis Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference KH Primary Assembly

    Genomic

    1. NC_020173.2 Reference KH Primary Assembly

      Range
      4234277..4238435 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version

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