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    ndx-7 Putative nudix hydrolase 7 [ Caenorhabditis elegans ]

    Gene ID: 183413, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ndx-7
    Official Full Name
    Putative nudix hydrolase 7
    Primary source
    WormBase:WBGene00003584
    Locus tag
    CELE_C43E11.7
    See related
    AllianceGenome:WB:WBGene00003584
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides and metal ion binding activity. Orthologous to human NUDT19 (nudix hydrolase 19). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ndx-7 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (4239091..4242727, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene NeurABin;Neurabin-1;Neurabin-2 Neighboring gene Tyrosine-protein phosphatase domain-containing protein Neighboring gene Exocyst complex component 7 Neighboring gene Tr-type G domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Caenorhabditis elegans Y87G2A.14 Nudix hydrolase is a peroxisomal coenzyme A diphosphatase. AbdelRaheim SR, et al. BMC Biochem, 2002 Mar 27. PMID 11943069, Free PMC Article
    2. SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells. Jackson J, et al. Mol Metab, 2022 Jul. PMID 35452878, Free PMC Article
    3. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    4. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative nudix hydrolase 7
    NP_491336.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      4239091..4242727 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_058935.8 → NP_491336.2  Putative nudix hydrolase 7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491336.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P91148
      Conserved Domains (1) summary
      pfam00293
      Location:10 → 173
      NUDIX; NUDIX domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P91148.2

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