Ppt2 palmitoyl-protein thioesterase 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Ppt2provided by RGD
Official Full Name: palmitoyl-protein thioesterase 2provided by RGD
Primary source: RGD:620375
See related: EnsemblRapid:ENSRNOG00000000435 AllianceGenome:RGD:620375
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable palmitoyl-(protein) hydrolase activity. Predicted to be involved in macromolecule depalmitoylation. Predicted to be active in extracellular region and lysosome. Orthologous to human PPT2 (palmitoyl-protein thioesterase 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 61.8), Kidney (RPKM 54.7) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 20p12

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (4117088..4137382)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (4112520..4132774)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	20	NC_005119.4 (4381455..4401638, complement)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

D20Yum62 (e-PCR)
- UniSTS:526103

BF405332 (e-PCR)
- UniSTS:247884

RH140482 (e-PCR)
- UniSTS:222554

RH124332 (e-PCR)
- UniSTS:161154

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables palmitoyl hydrolase activity	IEA Inferred from Electronic Annotation more info
enables palmitoyl hydrolase activity	ISO Inferred from Sequence Orthology more info
enables palmitoyl-(protein) hydrolase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in macromolecule depalmitoylation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in extracellular region	IBA Inferred from Biological aspect of Ancestor more info
is_active_in lysosome	IBA Inferred from Biological aspect of Ancestor more info
located_in lysosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: lysosomal thioesterase PPT2

NP_062240.1

EC 3.1.2.22

XP_006256079.2

EC 3.1.2.22

XP_006256081.1

EC 3.1.2.22

XP_006256082.1

EC 3.1.2.22

XP_006256084.1

EC 3.1.2.22

XP_006256085.1

EC 3.1.2.22

XP_008770984.1

EC 3.1.2.22

XP_038954969.1

EC 3.1.2.22

XP_038954973.1

EC 3.1.2.22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.