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    CG4646 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 36459, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG4646provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033810
    Locus tag
    Dmel_CG4646
    See related
    AllianceGenome:FB:FBgn0033810
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:SD14289; Dmel\CG4646
    Summary
    Predicted to enable zinc ion binding activity. Orthologous to human CZIB (CXXC motif containing zinc binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG4646 in Genome Data Viewer
    Location:
    49F10-49F10; 2-68 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (13219396..13220251, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (9106901..9107756, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene aquaporin Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene F-box synaptic protein Neighboring gene long non-coding RNA:CR43918 Neighboring gene DP transcription factor

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Pri peptides are mediators of ecdysone for the temporal control of development. Chanut-Delalande H, et al. Nat Cell Biol, 2014 Nov. PMID 25344753
    2. Quantitative and molecular genetic analyses of mutations increasing Drosophila life span. Magwire MM, et al. PLoS Genet, 2010 Jul 29. PMID 20686706, Free PMC Article
    3. SOD1 activity threshold and TOR signalling modulate VAP(P58S) aggregation via reactive oxygen species-induced proteasomal degradation in a Drosophila model of amyotrophic lateral sclerosis. Chaplot K, et al. Dis Model Mech, 2019 Feb 7. PMID 30635270, Free PMC Article
    4. Proteome-wide dataset supporting the study of ancient metazoan macromolecular complexes. Phanse S, et al. Data Brief, 2016 Mar. PMID 26870755, Free PMC Article
    5. Phylostratigraphic bias creates spurious patterns of genome evolution. Moyers BA, et al. Mol Biol Evol, 2015 Jan. PMID 25312911, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables zinc ion binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG4646-PA
    CG4646-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      13219396..13220251 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299453.1 → NP_001286382.1  uncharacterized protein Dmel_CG4646, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286382.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1Z9A2, Q8MRY1
      UniProtKB/TrEMBL
      A0A0B4LF92, I3VPX9
      Conserved Domains (1) summary
      pfam05907
      Location:6 → 158
      DUF866; Eukaryotic protein of unknown function (DUF866)

    2. NM_137004.4 → NP_610848.1  uncharacterized protein Dmel_CG4646, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610848.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A1Z9A2, Q8MRY1
      UniProtKB/TrEMBL
      A0A0B4LF92, I3VPX9
      Related
      FBpp0086877
      Conserved Domains (1) summary
      pfam05907
      Location:6 → 158
      DUF866; Eukaryotic protein of unknown function (DUF866)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A0A0B4LF92 A0A0B4LF92
    A1Z9A2.1 A1Z9A2

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