eIF3a eukaryotic translation initiation factor 3 subunit a [Drosophila melanogaster (fruit fly)] - Gene

Summary

Official Symbol: eIF3aprovided by FlyBase
Official Full Name: eukaryotic translation initiation factor 3 subunit aprovided by FlyBase
Primary source: FLYBASE:FBgn0037249
Locus tag: Dmel_CG9805
See related: AllianceGenome:FB:FBgn0037249
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Drosophila melanogaster
Lineage: Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as: anon-WO0118547.261; CG9805; Dmel\CG9805; eIF3; eIF3 S10; eIF3-s10; eIF3-S10; EIF3-S10; MMAP140
Summary: Predicted to enable mRNA binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in formation of cytoplasmic translation initiation complex; regulation of translational initiation; and translation reinitiation. Located in cytosol. Is expressed in adult brain cell body rind and adult head. Orthologous to human EIF3A (eukaryotic translation initiation factor 3 subunit A). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Annotation release	Status	Assembly	Chr	Location
Release 6.54	current	Release 6 plus ISO1 MT (GCF_000001215.4)	3R	NT_033777.3 (4429798..4433895, complement)
Release 5.57	previous assembly	Release 5 (GCF_000001215.2)	3R	NT_033777.2 (255520..259617, complement)

Chromosome 3R - NT_033777.3 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Annotated by Drosophila Heterochromatin Genome Project, Lawrence Berkeley National Lab, http://www.dhgp.org

Function	Evidence Code	Pubs
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
contributes_to translation initiation factor activity	IBA Inferred from Biological aspect of Ancestor more info
enables translation initiation factor activity	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Process	Evidence Code	Pubs
involved_in formation of cytoplasmic translation initiation complex	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of translational initiation	ISS Inferred from Sequence or Structural Similarity more info
involved_in translation reinitiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translational initiation	ISS Inferred from Sequence or Structural Similarity more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	HDA more info	PubMed
located_in cytosol	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of eukaryotic translation initiation factor 3 complex	IEA Inferred from Electronic Annotation more info
part_of eukaryotic translation initiation factor 3 complex	ISS Inferred from Sequence or Structural Similarity more info	PubMed
part_of eukaryotic translation initiation factor 3 complex, eIF3e	IBA Inferred from Biological aspect of Ancestor more info
part_of eukaryotic translation initiation factor 3 complex, eIF3m	IBA Inferred from Biological aspect of Ancestor more info
part_of multi-eIF complex	IBA Inferred from Biological aspect of Ancestor more info

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The following sections contain reference sequences that belong to a specific genome build. Explain