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    LOC103183072 ral guanine nucleotide dissociation stimulator [ Callorhinchus milii (elephant shark) ]

    Gene ID: 103183072, updated on 7-Dec-2023

    Summary

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    Gene symbol
    LOC103183072
    Gene description
    ral guanine nucleotide dissociation stimulator
    See related
    Ensembl:ENSCMIG00000002323
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Callorhinchus milii
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus
    Also known as
    ralgds
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    Genomic context

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    See LOC103183072 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    101 current IMCB_Cmil_1.0 (GCF_018977255.1) Unplaced Scaffold NW_024704749.1 (16147528..16191641)
    100 previous assembly Callorhinchus_milii-6.1.3 (GCF_000165045.1) Unplaced Scaffold NW_006890130.1 (2962155..3019496, complement)

    NW_024704749.1Genomic Context describing neighboring genes Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1-like Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 5 Neighboring gene cilia and flagella associated protein 157 Neighboring gene cerebral endothelial cell adhesion molecule

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequencing and analysis of full-length cDNAs, 5'-ESTs and 3'-ESTs from a cartilaginous fish, the elephant shark (Callorhinchus milii). Tan YY, et al. PLoS One, 2012. PMID 23056606, Free PMC Article
    2. Elephant shark genome provides unique insights into gnathostome evolution. Venkatesh B, et al. Nature, 2014 Jan 9. PMID 24402279, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Ras protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ral guanine nucleotide dissociation stimulator

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Callorhinchus milii Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference IMCB_Cmil_1.0 Primary Assembly

    Genomic

    1. NW_024704749.1 Reference IMCB_Cmil_1.0 Primary Assembly

      Range
      16147528..16191641
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_042337733.1 → XP_042193667.1  ral guanine nucleotide dissociation stimulator isoform X2

      UniProtKB/TrEMBL
      A0A4W3GJZ4
      Conserved Domains (3) summary
      smart00229
      Location:78 → 207
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00155
      Location:241 → 506
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
      cd17209
      Location:660 → 745
      RA_RalGDS; Ras-associating (RA) domain found in Ral guanine nucleotide dissociation stimulator (RalGDS) and similar proteins

    2. XM_007900330.2 → XP_007898521.1  ral guanine nucleotide dissociation stimulator isoform X1

      See identical proteins and their annotated locations for XP_007898521.1

      UniProtKB/TrEMBL
      A0A4W3GJZ4, V9K9F3
      Related
      ENSCMIP00000003998.1
      Conserved Domains (3) summary
      cd00153
      Location:698 → 783
      RalGDS_RA; Ubiquitin domain of RalGDS-like factor (RLF) and related proteins
      smart00229
      Location:116 → 245
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00155
      Location:279 → 544
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

    3. XM_007900333.2 → XP_007898524.1  ral guanine nucleotide dissociation stimulator isoform X4

      UniProtKB/TrEMBL
      A0A4W3GJZ4
      Conserved Domains (3) summary
      cd00153
      Location:640 → 725
      RalGDS_RA; Ubiquitin domain of RalGDS-like factor (RLF) and related proteins
      smart00229
      Location:116 → 245
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00155
      Location:279 → 544
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

    4. XM_007900331.2 → XP_007898522.1  ral guanine nucleotide dissociation stimulator isoform X3

      UniProtKB/TrEMBL
      A0A4W3GJZ4
      Related
      ENSCMIP00000004001.1
      Conserved Domains (3) summary
      cd00153
      Location:648 → 733
      RalGDS_RA; Ubiquitin domain of RalGDS-like factor (RLF) and related proteins
      smart00229
      Location:66 → 195
      RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
      cd00155
      Location:229 → 494
      RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    Nucleotide Protein
    Heading Accession and Version

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