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    PRSS12 serine protease 12 [ Nomascus leucogenys (northern white-cheeked gibbon) ]

    Gene ID: 100606810, updated on 8-Mar-2024

    Summary

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    Gene symbol
    PRSS12
    Gene description
    serine protease 12
    See related
    EnsemblRapid:ENSNLEG00000008859
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Nomascus leucogenys
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hylobatidae; Nomascus
    Orthologs
    human mouse all
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    Genomic context

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    See PRSS12 in Genome Data Viewer
    Location:
    chromosome: 7b
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    103 current Asia_NLE_v1 (GCF_006542625.1) 7b NC_044387.1 (37229202..37303660)
    102 previous assembly Nleu_3.0 (GCF_000146795.2) 7b NC_019822.1 (37688548..37767035)

    Chromosome 7b - NC_044387.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC115835963 Neighboring gene methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit Neighboring gene NADH dehydrogenase [ubiquinone] iron-sulfur protein 5-like Neighboring gene uncharacterized LOC100606467 Neighboring gene small nucleolar RNA SNORA24 Neighboring gene N-deacetylase and N-sulfotransferase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables serine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    neurotrypsin
    Names
    Neurotrypsin
    protease, serine 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Nomascus leucogenys Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Asia_NLE_v1 Primary Assembly

    Genomic

    1. NC_044387.1 Reference Asia_NLE_v1 Primary Assembly

      Range
      37229202..37303660
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030815755.1 → XP_030671615.1  neurotrypsin

      UniProtKB/TrEMBL
      G1RC72
      Related
      ENSNLEP00000010821.3, ENSNLET00000011350.3
      Conserved Domains (3) summary
      smart00130
      Location:99 → 164
      KR; Kringle domain
      smart00202
      Location:280 → 380
      SR; Scavenger receptor Cys-rich
      cd00190
      Location:631 → 872
      Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5G268.1 GenPept UniProtKB/Swiss-Prot:Q5G268

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