psme3 proteasome activator subunit 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: psme3provided by ZNC
Official Full Name: proteasome activator subunit 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-991110-19
See related: Ensembl:ENSDARG00000012234 AllianceGenome:ZFIN:ZDB-GENE-991110-19
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: unp310; PA28-gamma; wu:fb19c08
Summary: Predicted to enable endopeptidase activator activity. Acts upstream of or within sprouting angiogenesis. Predicted to be part of proteasome activator complex. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human PSME3 (proteasome activator subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 12

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	12	NC_007123.7 (27206738..27212835, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	12	NC_007123.6 (27115378..27121475, complement)

Chromosome 12 - NC_007123.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables endopeptidase activator activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of G1/S transition of mitotic cell cycle	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of proteasomal protein catabolic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within sprouting angiogenesis	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleoplasm	IBA Inferred from Biological aspect of Ancestor more info
part_of proteasome activator complex	IEA Inferred from Electronic Annotation more info
part_of proteasome complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: proteasome activator complex subunit 3

Names: proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131376.2 → NP_571451.2 proteasome activator complex subunit 3

See identical proteins and their annotated locations for NP_571451.2

Status: PROVISIONAL

Source sequence(s)

BC045495

UniProtKB/TrEMBL

A0A0R4ICU4, A0A8N7XJK1, Q6NWK5, Q7ZU20

Related

ENSDARP00000005578.7, ENSDART00000002835.9

Conserved Domains (2) summary

pfam02251
Location:12 → 68

PA28_alpha; Proteasome activator pa28 alpha subunit

pfam02252
Location:113 → 253

PA28_beta; Proteasome activator pa28 beta subunit