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    Dipk2b divergent protein kinase domain 2B [ Mus musculus (house mouse) ]

    Gene ID: 75905, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Dipk2bprovided by MGI
    Official Full Name
    divergent protein kinase domain 2Bprovided by MGI
    Primary source
    MGI:MGI:1923155
    See related
    Ensembl:ENSMUSG00000037358 AllianceGenome:MGI:1923155
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930578C19Rik
    Summary
    Predicted to be located in extracellular region. Orthologous to human DIPK2B (divergent protein kinase domain 2B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in subcutaneous fat pad adult (RPKM 2.2), lung adult (RPKM 1.9) and 19 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Dipk2b in Genome Data Viewer
    Location:
    X A1.3; X 13.73 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (18280406..18327657, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (18414167..18461419, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_46842 Neighboring gene STARR-seq mESC enhancer starr_46843 Neighboring gene STARR-seq mESC enhancer starr_46844 Neighboring gene STARR-seq mESC enhancer starr_46845 Neighboring gene STARR-seq mESC enhancer starr_46846 Neighboring gene STARR-seq mESC enhancer starr_46847 Neighboring gene nuclear encoded rRNA 5S 5 Neighboring gene up-regulated during skeletal muscle growth protein 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_46848 Neighboring gene STARR-seq mESC enhancer starr_46849 Neighboring gene STARR-seq mESC enhancer starr_46850 Neighboring gene STARR-seq mESC enhancer starr_46853 Neighboring gene STARR-seq mESC enhancer starr_46854 Neighboring gene STARR-seq mESC enhancer starr_46855 Neighboring gene STARR-seq mESC enhancer starr_46856 Neighboring gene STARR-seq mESC enhancer starr_46857 Neighboring gene STARR-seq mESC enhancer starr_46859 Neighboring gene heterogeneous nuclear ribonucleoprotein A3 pseudogene Neighboring gene microRNA 221

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    divergent protein kinase domain 2B
    Names
    UPF0672 protein CXorf36 homolog
    deleted in autism-related protein 1 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175228.4 → NP_780437.1  divergent protein kinase domain 2B precursor

      See identical proteins and their annotated locations for NP_780437.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the protein-coding transcript.
      Source sequence(s)
      AK085770, AK163928
      Consensus CDS
      CCDS30038.1
      UniProtKB/Swiss-Prot
      Q8C3I9
      Related
      ENSMUSP00000046567.5, ENSMUST00000044188.5
      Conserved Domains (1) summary
      pfam12260
      Location:213 → 393
      PIP49_C; Protein-kinase domain of FAM69

    RNA

    1. NR_132634.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains two alternate internal exons and two alternate exons at the 3' end compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK163928
      Related
      ENSMUST00000147039.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      18280406..18327657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527709.4 → XP_006527772.1  divergent protein kinase domain 2B isoform X1

      See identical proteins and their annotated locations for XP_006527772.1

      UniProtKB/TrEMBL
      Q3TQ46
      Conserved Domains (1) summary
      pfam12260
      Location:13 → 193
      PIP49_C; Protein-kinase domain of FAM69

    2. XM_006527708.5 → XP_006527771.1  divergent protein kinase domain 2B isoform X1

      See identical proteins and their annotated locations for XP_006527771.1

      UniProtKB/TrEMBL
      Q3TQ46
      Conserved Domains (1) summary
      pfam12260
      Location:13 → 193
      PIP49_C; Protein-kinase domain of FAM69

    RNA

    1. XR_386875.4 RNA Sequence

    2. XR_386876.4 RNA Sequence

    3. XR_878034.3 RNA Sequence

    4. XR_878033.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C3I9.1 GenPept UniProtKB/Swiss-Prot:Q8C3I9

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