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    Ccdc24 coiled-coil domain containing 24 [ Mus musculus (house mouse) ]

    Gene ID: 381546, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ccdc24provided by MGI
    Official Full Name
    coiled-coil domain containing 24provided by MGI
    Primary source
    MGI:MGI:2685874
    See related
    Ensembl:ENSMUSG00000078588 AllianceGenome:MGI:2685874
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1028
    Summary
    Acts upstream of or within blastocyst hatching. Is expressed in early conceptus. Orthologous to human CCDC24 (coiled-coil domain containing 24). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in testis adult (RPKM 58.6), lung adult (RPKM 21.4) and 14 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc24 in Genome Data Viewer
    Location:
    4 D1; 4 53.69 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (117725946..117729808, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (117869255..117872661, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 40232 Neighboring gene peptidylprolyl isomerase A pseudogene 4_1138.1 Neighboring gene solute carrier family 6 (neurotransmitter transporter, glycine), member 9 Neighboring gene UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 Neighboring gene predicted gene, 40233 Neighboring gene predicted gene 12841 Neighboring gene ATPase, H+ transporting, lysosomal V0 subunit B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos. Cui W, et al. Sci Rep, 2016 Nov 21. PMID 27869233, Free PMC Article
    2. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within blastocyst hatching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    coiled-coil domain-containing protein 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001034876.1 → NP_001030048.1  coiled-coil domain-containing protein 24

      See identical proteins and their annotated locations for NP_001030048.1

      Status: VALIDATED

      Source sequence(s)
      AK133118, BG088507, CD774819
      Consensus CDS
      CCDS51281.1
      UniProtKB/TrEMBL
      E9PUW8, Q3V0I8
      Related
      ENSMUSP00000102030.3, ENSMUST00000106422.9
      Conserved Domains (1) summary
      pfam15669
      Location:1 → 173
      CCDC24; Coiled-coil domain-containing protein 24 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      117725946..117729808 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503208.3 → XP_006503271.1  coiled-coil domain-containing protein 24 isoform X1

      Conserved Domains (1) summary
      pfam15669
      Location:1 → 116
      CCDC24; Coiled-coil domain-containing protein 24 family

    2. XM_006503209.2 → XP_006503272.1  coiled-coil domain-containing protein 24 isoform X2

      See identical proteins and their annotated locations for XP_006503272.1

      Conserved Domains (1) summary
      pfam15669
      Location:14 → 80
      CCDC24; Coiled-coil domain-containing protein 24 family

    3. XM_030253636.2 → XP_030109496.1  coiled-coil domain-containing protein 24 isoform X3

      UniProtKB/TrEMBL
      E9PUW8
      Related
      ENSMUSP00000129502.2, ENSMUST00000171052.8
      Conserved Domains (1) summary
      pfam15669
      Location:24 → 220
      CCDC24; Coiled-coil domain-containing protein 24 family
    Nucleotide Protein Strain
    Heading Accession and Version

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