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    Ctxn2 cortexin 2 [ Mus musculus (house mouse) ]

    Gene ID: 381418, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Ctxn2provided by MGI
    Official Full Name
    cortexin 2provided by MGI
    Primary source
    MGI:MGI:2139444
    See related
    Ensembl:ENSMUSG00000074872 AllianceGenome:MGI:2139444
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1638
    Summary
    Predicted to be located in membrane. Orthologous to human CTXN2 (cortexin 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E18 (RPKM 5.3), cerebellum adult (RPKM 3.4) and 5 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ctxn2 in Genome Data Viewer
    Location:
    2 F1; 2 61.21 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (124978534..124989763)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (125136066..125147843)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene myelin basic protein expression factor 2, repressor Neighboring gene STARR-seq mESC enhancer starr_05583 Neighboring gene predicted gene, 22352 Neighboring gene predicted gene, 46759 Neighboring gene solute carrier family 12, member 1 Neighboring gene STARR-positive B cell enhancer mm9_chr2:125014961-125015261 Neighboring gene predicted gene, 46760 Neighboring gene predicted gene 14002

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    2. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cortexin-2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001162934.2 → NP_001156406.3  cortexin-2

      Status: VALIDATED

      Source sequence(s)
      AL929451
      Consensus CDS
      CCDS50692.1
      UniProtKB/Swiss-Prot
      Q3URE8
      Related
      ENSMUSP00000158847.2, ENSMUST00000238377.2
      Conserved Domains (1) summary
      pfam11057
      Location:9 → 81
      Cortexin; Cortexin of kidney

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      124978534..124989763
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006499833.4 → XP_006499896.1  cortexin-2 isoform X1

      See identical proteins and their annotated locations for XP_006499896.1

      UniProtKB/TrEMBL
      A0A0R4J179
      Related
      ENSMUSP00000158834.2, ENSMUST00000238754.2
      Conserved Domains (1) summary
      pfam11057
      Location:10 → 82
      Cortexin; Cortexin of kidney

    2. XM_006499835.3 → XP_006499898.1  cortexin-2 isoform X1

      See identical proteins and their annotated locations for XP_006499898.1

      UniProtKB/TrEMBL
      A0A0R4J179
      Conserved Domains (1) summary
      pfam11057
      Location:10 → 82
      Cortexin; Cortexin of kidney

    3. XM_006499834.5 → XP_006499897.1  cortexin-2 isoform X1

      See identical proteins and their annotated locations for XP_006499897.1

      UniProtKB/TrEMBL
      A0A0R4J179
      Conserved Domains (1) summary
      pfam11057
      Location:10 → 82
      Cortexin; Cortexin of kidney
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3URE8.2 GenPept UniProtKB/Swiss-Prot:Q3URE8

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