Stard3nl STARD3 N-terminal like [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Stard3nlprovided by RGD
Official Full Name: STARD3 N-terminal likeprovided by RGD
Primary source: RGD:1308633
See related: EnsemblRapid:ENSRNOG00000052429 AllianceGenome:RGD:1308633
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable cholesterol binding activity and protein homodimerization activity. Predicted to be involved in cholesterol transport and vesicle tethering to endoplasmic reticulum. Predicted to be located in endosome and organelle membrane contact site. Predicted to be active in endoplasmic reticulum-endosome membrane contact site and late endosome membrane. Predicted to colocalize with endoplasmic reticulum membrane. Orthologous to human STARD3NL (STARD3 N-terminal like). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Brain (RPKM 130.7), Lung (RPKM 122.5) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 17q11

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (50278859..50312864)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (45583278..45617226)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (47662553..47696453)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MLN64 has roles with StAR, and SCP-2 in regulating bile acid synthesis
Title: Effect of increasing the expression of cholesterol transporters (StAR, MLN64, and SCP-2) on bile acid synthesis.

Submit: New GeneRIF Correction

General gene information

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Markers

AW124774 (e-PCR)
- UniSTS:185967

RH129904 (e-PCR)
- UniSTS:213192

RH129383 (e-PCR)
- UniSTS:212690

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables cholesterol binding	IBA Inferred from Biological aspect of Ancestor more info
enables cholesterol binding	ISO Inferred from Sequence Orthology more info
enables protein homodimerization activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in cholesterol transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle tethering to endoplasmic reticulum	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle tethering to endoplasmic reticulum	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
colocalizes_with endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info
is_active_in endoplasmic reticulum-endosome membrane contact site	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum-endosome membrane contact site	ISO Inferred from Sequence Orthology more info
located_in endosome	ISO Inferred from Sequence Orthology more info
located_in intracellular membrane-bounded organelle	ISO Inferred from Sequence Orthology more info
is_active_in late endosome membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in late endosome membrane	ISO Inferred from Sequence Orthology more info
located_in organelle membrane contact site	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: STARD3 N-terminal-like protein

Names: MLN64 N-terminal domain homolog; MLN64 N-terminal homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.