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    PF3D7_0520900 adenosylhomocysteinase [ Plasmodium falciparum 3D7 ]

    Gene ID: 813025, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_0520900
    Gene description
    adenosylhomocysteinase
    Locus tag
    PF3D7_0520900
    See related
    PlasmoDB:PF3D7_0520900; VEuPathDB:PF3D7_0520900
    Gene type
    protein coding
    RNA name
    adenosylhomocysteinase
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_0520900 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    1
    Sequence:
    Chromosome: 5; NC_004326.2 (857038..858477)

    Chromosome 5 - NC_004326.2Genomic Context describing neighboring genes Neighboring gene CDC73 domain-containing protein, putative Neighboring gene conserved protein, unknown function Neighboring gene conserved Plasmodium protein, unknown function Neighboring gene conserved Plasmodium protein, unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_004326.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Three-dimensional structure of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum. Tanaka N, et al. Nucleic Acids Symp Ser (Oxf), 2004. PMID 17150588
    2. Structure, evolution, and inhibitor interaction of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum. Bujnicki JM, et al. Proteins, 2003 Sep 1. PMID 12910461
    3. The interactome of 2-Cys peroxiredoxins in Plasmodium falciparum. Brandstaedter C, et al. Sci Rep, 2019 Sep 19. PMID 31537845, Free PMC Article
    4. Proteome mapping of Plasmodium: identification of the P. yoelii remodellome. Siau A, et al. Sci Rep, 2016 Aug 9. PMID 27503796, Free PMC Article
    5. A network-based approach reveals novel invasion and Maurer's clefts-related proteins in Plasmodium falciparum. Das D, et al. Mol Omics, 2019 Dec 2. PMID 31631203

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. The crystal structure of PfSAHH, is reported.
      Title: Three-dimensional structure of S-adenosyl-L-homocysteine hydrolase from Plasmodium falciparum.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables adenosylhomocysteinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Maurer's cleft RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in intracellular anatomical structure ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    adenosylhomocysteinase
    XP_001351767.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004326.2 Reference assembly

      Range
      857038..858477
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001351731.1 → XP_001351767.1  adenosylhomocysteinase [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001351767.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P50250, Q7K6A6, Q8MUG1
      UniProtKB/TrEMBL
      A0A024UXC3, A0A024VU74, A0A024WBE1, A0A024WV40, A0A024XCE4, A0A0L0CUW5, A0A0L1I8R7, A0A0L7KFY1, A0A0L7LZQ5, W4IMJ9, W4IUH2, W7FC21, W7G037, W7JGE5, W7JYE1
      Conserved Domains (1) summary
      PTZ00075
      Location:3 → 479
      PTZ00075; Adenosylhomocysteinase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    1V8B_A.1
    1V8B_B.1
    1V8B_C.1
    1V8B_D.1
    P50250.2

    Gene LinkOut

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