Spata20 spermatogenesis associated 20 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Spata20provided by RGD
Official Full Name: spermatogenesis associated 20provided by RGD
Primary source: RGD:735087
See related: EnsemblRapid:ENSRNOG00000003273 AllianceGenome:RGD:735087
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: Ssp411
Summary: Predicted to be involved in carbohydrate metabolic process; cell differentiation; and spermatogenesis. Predicted to be located in mitochondrion. Orthologous to human SPATA20 (spermatogenesis associated 20). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Restricted expression toward (RPKM 1212.4) See more
Orthologs: human mouse all
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Genomic context

Location:: 10q26

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (79924407..79932351, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (79427525..79435472, complement)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (82202619..82217260, complement)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

SSP411 may play a role in sperm maturation, fertilization, and/or embryo development, as has been shown in thioredoxin family
Title: Cloning and characterization of rat spermatid protein SSP411: a thioredoxin-like protein.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info
involved_in spermatogenesis	IEA Inferred from Electronic Annotation more info
involved_in spermatogenesis	NAS Non-traceable Author Statement more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	ISO Inferred from Sequence Orthology more info	PubMed

General protein information

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Preferred Names: spermatogenesis-associated protein 20

Names: sperm protein SSP411; sperm-specific protein 411

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199402.1 → NP_955434.1 spermatogenesis-associated protein 20

See identical proteins and their annotated locations for NP_955434.1

Status: PROVISIONAL

Source sequence(s)

AY438568

UniProtKB/Swiss-Prot

Q6T393

UniProtKB/TrEMBL

F1LSR7

Related

ENSRNOP00000004377.3, ENSRNOT00000004377.6

Conserved Domains (2) summary

COG1331
Location:59 → 787

YyaL; Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains [General function prediction only]

pfam03190
Location:66 → 226

Thioredox_DsbH; Protein of unknown function, DUF255

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086028.1 Reference GRCr8

Range

79924407..79932351 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006247200.4 → XP_006247262.1 spermatogenesis-associated protein 20 isoform X1

See identical proteins and their annotated locations for XP_006247262.1

UniProtKB/TrEMBL

A6HI51, F1LSR7

Conserved Domains (2) summary

COG1331
Location:15 → 743

YyaL; Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains [General function prediction only]

pfam03190
Location:22 → 182

Thioredox_DsbH; Protein of unknown function, DUF255