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    QKI QKI, KH domain containing RNA binding [ Bos taurus (domestic cattle) ]

    Gene ID: 493722, updated on 27-Dec-2024

    Summary

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    Official Symbol
    QKIprovided by VGNC
    Official Full Name
    QKI, KH domain containing RNA bindingprovided by VGNC
    Primary source
    VGNC:VGNC:33597
    See related
    Ensembl:ENSBTAG00000011593
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Bos taurus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
    Also known as
    BqkI
    Orthologs
    human mouse all
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    Genomic context

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    See QKI in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_12 current ARS-UCD2.0 (GCF_002263795.3) 9 NC_037336.1 (98820543..98980967)

    Chromosome 9 - NC_037336.1Genomic Context describing neighboring genes Neighboring gene parkin coregulated Neighboring gene uncharacterized LOC107132796 Neighboring gene uncharacterized LOC112448145 Neighboring gene uncharacterized LOC101908046 Neighboring gene uncharacterized LOC101908095

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037336.1 Chromosome 9 Reference ARS-UCD2.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Dominette sequence data
    • BioProject: PRJNA294306
    • Analysis date: Tue Dec 17 08:57:05 2024

    Bibliography

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    Related articles in PubMed

    1. Nucleotide sequence of complementary DNA encoding for quaking protein of cow, horse and pig. Murata T, et al. DNA Seq, 2005 Aug. PMID 16147890
    2. A whole-genome assembly of the domestic cow, Bos taurus. Zimin AV, et al. Genome Biol, 2009. PMID 19393038, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables mRNA binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in regulation of mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    KH domain-containing RNA-binding protein QKI
    Names
    protein quaking
    quaking homolog, KH domain RNA binding
    quaking protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007817.1 → NP_001007818.1  KH domain-containing RNA-binding protein QKI

      See identical proteins and their annotated locations for NP_001007818.1

      Status: PROVISIONAL

      Source sequence(s)
      AB177986
      UniProtKB/Swiss-Prot
      Q5W9D7
      Related
      ENSBTAP00000048511.3, ENSBTAT00000054202.4
      Conserved Domains (4) summary
      PHA03247
      Location:211 → 314
      PHA03247; large tegument protein UL36; Provisional
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      pfam16551
      Location:312 → 341
      Quaking_NLS; Putative nuclear localization signal of quaking
      cd22465
      Location:81 → 183
      KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

    RefSeqs of Annotated Genomes: GCF_002263795.3-RS_2024_12

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ARS-UCD2.0 Primary Assembly

    Genomic

    1. NC_037336.1 Reference ARS-UCD2.0 Primary Assembly

      Range
      98820543..98980967
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_024996433.2 → XP_024852201.1  KH domain-containing RNA-binding protein QKI isoform X4

      UniProtKB/TrEMBL
      A0AAA9SAY6
      Related
      ENSBTAP00000083263.1, ENSBTAT00000122459.1
      Conserved Domains (3) summary
      cd02395
      Location:117 → 239
      SF1_like-KH; Splicing factor 1 (SF1) K homology RNA-binding domain (KH). Splicing factor 1 (SF1) specifically recognizes the intron branch point sequence (BPS) UACUAAC in the pre-mRNA transcripts during spliceosome assembly. We show that the KH-QUA2 region of SF1 ...
      pfam16551
      Location:348 → 375
      Quaking_NLS; Putative nuclear localization signal of quaking
      pfam16544
      Location:10 → 102
      STAR_dimer; Homodimerisation region of STAR domain protein

    2. XM_024996431.2 → XP_024852199.1  KH domain-containing RNA-binding protein QKI isoform X5

      UniProtKB/TrEMBL
      A0A3Q1MA86
      Related
      ENSBTAP00000067509.2, ENSBTAT00000069603.2
      Conserved Domains (3) summary
      PRK14951
      Location:210 → 281
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      cd22465
      Location:81 → 183
      KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

    3. XM_024996434.2 → XP_024852202.1  KH domain-containing RNA-binding protein QKI isoform X6

      Conserved Domains (3) summary
      PRK14951
      Location:210 → 281
      PRK14951; DNA polymerase III subunits gamma and tau; Provisional
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      cd22465
      Location:81 → 183
      KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

    4. XM_024996432.2 → XP_024852200.1  KH domain-containing RNA-binding protein QKI isoform X2

      Conserved Domains (3) summary
      PRK14950
      Location:195 → 289
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      cd22465
      Location:81 → 183
      KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

    5. XM_024996430.2 → XP_024852198.1  KH domain-containing RNA-binding protein QKI isoform X1

      Conserved Domains (4) summary
      PRK14950
      Location:195 → 305
      PRK14950; DNA polymerase III subunits gamma and tau; Provisional
      pfam16544
      Location:10 → 66
      STAR_dimer; Homodimerization region of STAR domain protein
      pfam16551
      Location:304 → 333
      Quaking_NLS; Putative nuclear localization signal of quaking
      cd22465
      Location:81 → 183
      KH-I_Hqk; type I K homology (KH) RNA-binding domain found in protein quaking (Hqk) and similar proteins

    6. XM_059889596.1 → XP_059745579.1  KH domain-containing RNA-binding protein QKI isoform X3

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5W9D7.1 GenPept UniProtKB/Swiss-Prot:Q5W9D7

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