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    MARCHF1 membrane associated ring-CH-type finger 1 [ Gallus gallus (chicken) ]

    Gene ID: 422420, updated on 17-Aug-2024

    Summary

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    Official Symbol
    MARCHF1provided by CGNC
    Official Full Name
    membrane associated ring-CH-type finger 1provided by CGNC
    Primary source
    CGNC:7247
    See related
    Ensembl:ENSGALG00010007980
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    MARCH1; Mar-01
    Orthologs
    human mouse all
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    Genomic context

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    See MARCHF1 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (22884603..23105005, complement)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (22951307..23171670, complement)

    Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121113208 Neighboring gene translation machinery associated 16 homolog Neighboring gene uncharacterized LOC121110791 Neighboring gene apelin receptor early endogenous ligand

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables MHC protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in antigen processing and presentation of peptide antigen via MHC class II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in immune response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein polyubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in early endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in late endosome membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in lysosome IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase MARCHF1
    Names
    E3 ubiquitin-protein ligase MARCH1
    membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
    NP_001273153.1
    XP_004940970.2
    XP_015140777.1
    XP_015140778.1
    XP_046771842.1
    XP_046771843.1
    XP_046771844.1
    XP_046771845.1
    XP_046796007.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001286224.1 → NP_001273153.1  E3 ubiquitin-protein ligase MARCHF1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000071
      UniProtKB/TrEMBL
      A0A8V0XQU6, F1NSN9
      Related
      ENSGALP00010010574.1, ENSGALT00010019025.1
      Conserved Domains (1) summary
      cd16698
      Location:76 → 127
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      22884603..23105005 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004940913.5 → XP_004940970.2  E3 ubiquitin-protein ligase MARCHF1 isoform X2

      Conserved Domains (1) summary
      cd16698
      Location:228 → 279
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    2. XM_015285291.4 → XP_015140777.1  E3 ubiquitin-protein ligase MARCHF1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y382
      Conserved Domains (1) summary
      cd16698
      Location:324 → 375
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    3. XM_015285292.4 → XP_015140778.1  E3 ubiquitin-protein ligase MARCHF1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y382
      Conserved Domains (1) summary
      cd16698
      Location:324 → 375
      RING_CH-C4HC3_MARCH1_like; RING-CH finger, H2 subclass (C4HC3-type), found in membrane-associated RING finger protein MARCH1, MARCH8, and similar proteins

    4. XM_046940051.1 → XP_046796007.1  E3 ubiquitin-protein ligase MARCHF1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y382
      Related
      ENSGALP00010010572.1, ENSGALT00010019023.1

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      22951307..23171670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046915889.1 → XP_046771845.1  E3 ubiquitin-protein ligase MARCHF1 isoform X2

    2. XM_046915886.1 → XP_046771842.1  E3 ubiquitin-protein ligase MARCHF1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y382

    3. XM_046915887.1 → XP_046771843.1  E3 ubiquitin-protein ligase MARCHF1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y382

    4. XM_046915888.1 → XP_046771844.1  E3 ubiquitin-protein ligase MARCHF1 isoform X1

      UniProtKB/TrEMBL
      A0A8V0Y382
    Nucleotide Protein
    Heading Accession and Version

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