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These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_001270695.1 → NP_001257624.1 rho GTPase-activating protein 12 isoform 2
See identical proteins and their annotated locations for NP_001257624.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an alternate in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
- Source sequence(s)
-
AL137485, AL390715, BC094719, BM693575, DB062438
- Consensus CDS
-
CCDS59216.1
- UniProtKB/TrEMBL
-
A0A2X0TVR3
- Related
- ENSP00000379448.4, ENST00000396144.8
- Conserved Domains (5) summary
-
- cd12070
Location:15 → 74
- SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
- cd00201
Location:268 → 298
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd04403
Location:649 → 834
- RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
- cd13233
Location:460 → 571
- PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
- pfam16618
Location:71 → 266
- SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
-
NM_001270696.2 → NP_001257625.1 rho GTPase-activating protein 12 isoform 3
See identical proteins and their annotated locations for NP_001257625.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (3, also known as ARHGAP12a) lacks two alternate in-frame exons in the coding region, compared to variant 1. The encoded isoform (3) is shorter than isoform 1.
- Source sequence(s)
-
AL137485, AL390715, AY033594, BM693575
- Consensus CDS
-
CCDS59215.1
- UniProtKB/TrEMBL
-
B3KR88
- Related
- ENSP00000364399.5, ENST00000375250.9
- Conserved Domains (6) summary
-
- cd12070
Location:15 → 74
- SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
- cd00201
Location:268 → 298
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd04403
Location:624 → 809
- RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
- cd13233
Location:435 → 546
- PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
- pfam00169
Location:449 → 544
- PH; PH domain
- pfam16618
Location:71 → 266
- SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
-
NM_001270697.1 → NP_001257626.1 rho GTPase-activating protein 12 isoform 4
See identical proteins and their annotated locations for NP_001257626.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (4) lacks an alternate in-frame exon in the coding region, compared to variant 1. The encoded isoform (4) is shorter than isoform 1.
- Source sequence(s)
-
AL137485, AL390715, BC115362, BM693575, DB062438
- Consensus CDS
-
CCDS73082.1
- UniProtKB/TrEMBL
- A0A2X0TVR3, Q1RLN5
- Related
- ENSP00000364394.5, ENST00000375245.8
- Conserved Domains (5) summary
-
- cd12070
Location:15 → 74
- SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
- cd00201
Location:268 → 298
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd04403
Location:607 → 792
- RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
- cd13233
Location:418 → 529
- PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
- pfam16618
Location:71 → 266
- SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
-
NM_001270698.2 → NP_001257627.1 rho GTPase-activating protein 12 isoform 5
Status: REVIEWED
- Description
- Transcript Variant: This variant (5) lacks three alternate in-frame exons in the coding region, compared to variant 1. The encoded isoform (5) is shorter than isoform 1.
- Source sequence(s)
-
AK315066, AL137485, AL390715, BM693575, DB062438
- UniProtKB/TrEMBL
-
B3KR88
- Conserved Domains (6) summary
-
- cd12070
Location:15 → 74
- SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
- cd00201
Location:268 → 298
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd04403
Location:577 → 762
- RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
- cd13233
Location:388 → 499
- PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
- pfam00169
Location:402 → 497
- PH; PH domain
- pfam16618
Location:71 → 266
- SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
-
NM_001270699.1 → NP_001257628.1 rho GTPase-activating protein 12 isoform 6
See identical proteins and their annotated locations for NP_001257628.1
Status: REVIEWED
- Description
- Transcript Variant: This variant (6) differs in the 5' UTR and lacks two alternate in-frame exons in the coding region, compared to variant 1. The encoded isoform (6) is shorter than isoform 1.
- Source sequence(s)
-
AL137485, AL390715, AL834250, AY033595, BM693575
- Consensus CDS
-
CCDS59214.1
- UniProtKB/TrEMBL
-
A0A2X0TVR3
- Related
- ENSP00000310984.4, ENST00000311380.8
- Conserved Domains (6) summary
-
- cd12070
Location:15 → 74
- SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
- cd00201
Location:268 → 298
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd04403
Location:602 → 787
- RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
- cd13233
Location:413 → 524
- PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
- pfam00169
Location:427 → 522
- PH; PH domain
- pfam16618
Location:71 → 266
- SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
-
NM_018287.7 → NP_060757.4 rho GTPase-activating protein 12 isoform 1
See identical proteins and their annotated locations for NP_060757.4
Status: REVIEWED
- Description
- Transcript Variant: This variant (1, also known as ARHGAP12b) represents the longest transcript and encodes the longest isoform (1).
- Source sequence(s)
-
AL137485, AL390715, AY033595, BM693575
- Consensus CDS
-
CCDS7170.1
- UniProtKB/Swiss-Prot
- B1ANY0, B1ANY1, B1ANY2, Q504X1, Q86UB3, Q8IWW6, Q8IWW7, Q8N3L1, Q9NT76
- UniProtKB/TrEMBL
-
A0A2X0TVR3
- Related
- ENSP00000345808.2, ENST00000344936.7
- Conserved Domains (6) summary
-
- cd12070
Location:15 → 74
- SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
- cd00201
Location:268 → 298
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd04403
Location:654 → 839
- RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
- cd13233
Location:465 → 576
- PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
- pfam00169
Location:479 → 574
- PH; PH domain
- pfam16618
Location:71 → 266
- SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000010.11 Reference GRCh38.p14 Primary Assembly
- Range
-
31805398..31928876 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_017016954.3 → XP_016872443.1 rho GTPase-activating protein 12 isoform X4
- UniProtKB/TrEMBL
-
B3KR88
-
XM_047426021.1 → XP_047281977.1 rho GTPase-activating protein 12 isoform X3
- UniProtKB/TrEMBL
-
A0A2X0TVR3
-
XM_011519761.3 → XP_011518063.1 rho GTPase-activating protein 12 isoform X2
- UniProtKB/TrEMBL
-
A0A2X0TVR3
- Conserved Domains (6) summary
-
- cd12070
Location:15 → 74
- SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
- cd00201
Location:268 → 298
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd04403
Location:580 → 765
- RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
- cd13233
Location:391 → 502
- PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
- pfam00169
Location:405 → 500
- PH; PH domain
- pfam16618
Location:71 → 266
- SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
-
XM_005252644.3 → XP_005252701.1 rho GTPase-activating protein 12 isoform X1
See identical proteins and their annotated locations for XP_005252701.1
- UniProtKB/TrEMBL
-
A0A2X0TVR3
- Conserved Domains (6) summary
-
- cd12070
Location:15 → 74
- SH3_ARHGAP12; Src Homology 3 domain of Rho GTPase-activating protein 12
- cd00201
Location:268 → 298
- WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
- cd04403
Location:602 → 787
- RhoGAP_ARHGAP27_15_12_9; RhoGAP_ARHGAP27_15_12_9: GTPase-activator protein (GAP) domain for Rho-like GTPases found in ARHGAP27 (also called CAMGAP1), ARHGAP15, 12 and 9-like proteins; This subgroup of ARHGAPs are multidomain proteins that contain RhoGAP, PH, SH3 and WW domains. ...
- cd13233
Location:413 → 524
- PH_ARHGAP9-like; Beta-spectrin pleckstrin homology (PH) domain
- pfam00169
Location:427 → 522
- PH; PH domain
- pfam16618
Location:71 → 266
- SH3-WW_linker; Linker region between SH3 and WW domains on ARHGAP12
Alternate T2T-CHM13v2.0
Genomic
-
NC_060934.1 Alternate T2T-CHM13v2.0
- Range
-
31836817..31960265 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_054367199.1 → XP_054223174.1 rho GTPase-activating protein 12 isoform X4
- UniProtKB/TrEMBL
-
B3KR88
-
XM_054367198.1 → XP_054223173.1 rho GTPase-activating protein 12 isoform X3
- UniProtKB/TrEMBL
-
A0A2X0TVR3
-
XM_054367197.1 → XP_054223172.1 rho GTPase-activating protein 12 isoform X2
- UniProtKB/TrEMBL
-
A0A2X0TVR3
-
XM_054367196.1 → XP_054223171.1 rho GTPase-activating protein 12 isoform X1
- UniProtKB/TrEMBL
-
A0A2X0TVR3