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    nup58 nucleoporin 58 [ Danio rerio (zebrafish) ]

    Gene ID: 406510, updated on 4-Jan-2025

    Summary

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    Official Symbol
    nup58provided by ZNC
    Official Full Name
    nucleoporin 58provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-2326
    See related
    Ensembl:ENSDARG00000033965 AllianceGenome:ZFIN:ZDB-GENE-040426-2326
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    nupl1; zgc:85711; wu:fc45d07; wu:fi14f12; wu:fi21d10; zgc:113941
    Summary
    Predicted to enable nuclear localization sequence binding activity. Predicted to be a structural constituent of nuclear pore. Predicted to act upstream of or within mRNA transport; nucleocytoplasmic transport; and protein transport. Part of nuclear pore. Orthologous to human NUP58 (nucleoporin 58). [provided by Alliance of Genome Resources, Jan 2025]
    Orthologs
    human mouse all
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    Genomic context

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    See nup58 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (25008211..25030189, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (24863037..24885047, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 51 member A Neighboring gene zinc finger DHHC-type palmitoyltransferase 20b Neighboring gene myotubularin related protein 6 Neighboring gene APC membrane recruitment protein 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Control over the morphology and segregation of Zebrafish germ cell granules during embryonic development. Strasser MJ, et al. BMC Dev Biol, 2008 May 28. PMID 18507824, Free PMC Article
    2. Duplication and subfunctionalisation of the general transcription factor IIIA (gtf3a) gene in teleost genomes, with ovarian specific transcription of gtf3ab. Rojo-Bartolomé I, et al. PLoS One, 2020. PMID 31999691, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC113941

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nuclear localization sequence binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mRNA transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within nucleocytoplasmic transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of nuclear pore IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of nuclear pore IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nucleoporin p58/p45
    Names
    nucleoporin like 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213229.1 → NP_998394.1  nucleoporin p58/p45

      Status: PROVISIONAL

      Source sequence(s)
      BC068367
      UniProtKB/TrEMBL
      Q6NUZ9
      Related
      ENSDARP00000022894.7, ENSDART00000019350.9
      Conserved Domains (2) summary
      pfam15967
      Location:64 → 567
      Nucleoporin_FG2; Nucleoporin FG repeated region
      cl02193
      Location:355 → 449
      VirB5_like; VirB5 protein family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      25008211..25030189 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005162682.5 → XP_005162739.1  nucleoporin p58/p45 isoform X2

      UniProtKB/TrEMBL
      A0A8M2B9L0
      Conserved Domains (2) summary
      pfam15967
      Location:64 → 599
      Nucleoporin_FG2; Nucleoporin FG repeated region
      cl02193
      Location:355 → 449
      VirB5_like; VirB5 protein family

    2. XM_005162685.4 → XP_005162742.1  nucleoporin p58/p45 isoform X5

      UniProtKB/TrEMBL
      A0A8M2B9M4
      Conserved Domains (1) summary
      pfam15967
      Location:64 → 540
      Nucleoporin_FG2; Nucleoporin FG repeated region

    3. XM_005162684.4 → XP_005162741.1  nucleoporin p58/p45 isoform X3

      UniProtKB/TrEMBL
      A0A8M2B9X4
      Conserved Domains (2) summary
      pfam15967
      Location:64 → 568
      Nucleoporin_FG2; Nucleoporin FG repeated region
      cl02193
      Location:356 → 450
      VirB5_like; VirB5 protein family

    4. XM_005162681.4 → XP_005162738.1  nucleoporin p58/p45 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B9R7
      Conserved Domains (2) summary
      pfam15967
      Location:64 → 600
      Nucleoporin_FG2; Nucleoporin FG repeated region
      cl02193
      Location:356 → 450
      VirB5_like; VirB5 protein family

    5. XM_021470124.2 → XP_021325799.1  nucleoporin p58/p45 isoform X4

      UniProtKB/TrEMBL
      A0A8M9PLM6
      Conserved Domains (1) summary
      cl25599
      Location:31 → 477
      Nucleoporin_FG2; Nucleoporin FG repeated region
    Nucleotide Protein Strain
    Heading Accession and Version

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