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    zbtb22b zinc finger and BTB domain containing 22b [ Danio rerio (zebrafish) ]

    Gene ID: 64809, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zbtb22bprovided by ZNC
    Official Full Name
    zinc finger and BTB domain containing 22bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-010110-4
    See related
    Ensembl:ENSDARG00000003251 AllianceGenome:ZFIN:ZDB-GENE-010110-4
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    BING1; zbtb22; znf297; fj98b06; wu:fj98b06
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Orthologous to human ZBTB22 (zinc finger and BTB domain containing 22). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See zbtb22b in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (7001171..7006697)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (7082246..7087772)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 384 a Neighboring gene kinesin family member C1 Neighboring gene death-domain associated protein Neighboring gene TAP binding protein (tapasin), tandem duplicate 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Structure, linkage mapping and expression of the heart-type fatty acid-binding protein gene (fabp3 ) from zebrafish (Danio rerio). Liu RZ, et al. Eur J Biochem, 2003 Aug. PMID 12869198
    2. Identification of seven genes in the major histocompatibility complex class I region of the zebrafish. Sültmann H, et al. Scand J Immunol, 2000 Jun. PMID 10849368
    3. Characterization of novel zebrafish MHC class I U lineage genes and their haplotype. Honjo Y, et al. Dev Comp Immunol, 2021 Mar. PMID 33279476
    4. Multiple divergent haplotypes express completely distinct sets of class I MHC genes in zebrafish. McConnell SC, et al. Immunogenetics, 2014 Mar. PMID 24291825, Free PMC Article
    5. Characterization of the six zebrafish clade B fibrillar procollagen genes, with evidence for evolutionarily conserved alternative splicing within the pro-alpha1(V) C-propeptide. Hoffman GG, et al. Matrix Biol, 2010 May. PMID 20102740, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger and BTB domain-containing protein 22b
    Names
    zinc finger and BTB domain containing 22
    zinc finger protein 297

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001311347.1 → NP_001298276.1  zinc finger and BTB domain-containing protein 22b

      Status: VALIDATED

      Source sequence(s)
      EH594603, FP102097
      UniProtKB/TrEMBL
      A0A8M1P6X4, Q1LUU5
      Related
      ENSDARP00000103900.4, ENSDART00000110366.6
      Conserved Domains (5) summary
      smart00225
      Location:44 → 135
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:490 → 509
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:515 → 537
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:33 → 134
      BTB; BTB/POZ domain
      pfam13465
      Location:529 → 552
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      7001171..7006697
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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