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    Apoc3 apolipoprotein C3 [ Heterocephalus glaber (naked mole-rat) ]

    Gene ID: 101725083, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Apoc3
    Gene description
    apolipoprotein C3
    See related
    Ensembl:ENSHGLG00000019030
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Heterocephalus glaber
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Heterocephalus
    Also known as
    Apo-CIII; ApoC-III
    Orthologs
    human mouse all
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    Genomic context

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    See Apoc3 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    102 current HetGla_female_1.0 (GCF_000247695.1) Unplaced Scaffold NW_004624784.1 (12244565..12246790)

    NW_004624784.1Genomic Context describing neighboring genes Neighboring gene apolipoprotein A5 Neighboring gene apolipoprotein A4 Neighboring gene apolipoprotein A1 Neighboring gene serine/threonine-protein kinase SIK3-like Neighboring gene SIK family kinase 3

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004624784 Unplaced Scaffold Reference HetGla_female_1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables high-density lipoprotein particle receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables lipase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cholesterol homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipoprotein metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of high-density lipoprotein particle clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of lipoprotein lipase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of low-density lipoprotein particle clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of triglyceride catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in negative regulation of very-low-density lipoprotein particle clearance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in triglyceride homeostasis IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of chylomicron IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of intermediate-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of spherical high-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of very-low-density lipoprotein particle IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    apolipoprotein C-III

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Heterocephalus glaber Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HetGla_female_1.0 Primary Assembly

    Genomic

    1. NW_004624784.1 Reference HetGla_female_1.0 Primary Assembly

      Range
      12244565..12246790
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_004856643.3 → XP_004856700.1  apolipoprotein C-III

      See identical proteins and their annotated locations for XP_004856700.1

      UniProtKB/Swiss-Prot
      G5BQH4
      UniProtKB/TrEMBL
      A0A0P6JT95
      Related
      ENSHGLP00000026753.1, ENSHGLT00000026991.1
      Conserved Domains (1) summary
      pfam05778
      Location:23 → 96
      Apo-CIII; Apolipoprotein CIII (Apo-CIII)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    G5BQH4.2 GenPept UniProtKB/Swiss-Prot:G5BQH4

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