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    lipA lipoyl synthase [ Halorubrum lacusprofundi ATCC 49239 ]

    Gene ID: 7400619, updated on 2-Dec-2024

    Summary

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    Gene symbol
    lipA
    Gene description
    lipoyl synthase
    Locus tag
    HLAC_RS10440
    Gene type
    protein coding
    Organism
    Halorubrum lacusprofundi ATCC 49239 (strain: ATCC 49239, culture-collection: ATCC:49239, type-material: type strain of Halorubrum lacusprofundi)
    Lineage
    Archaea; Methanobacteriati; Methanobacteriota; Stenosarchaea group; Halobacteria; Halobacteriales; Haloferacaceae; Halorubrum
    Old locus tag
    Hlac_2099
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    Genomic context

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    Location:
    chromosome: 1
    Sequence:
    Chromosome: 1; NC_012029.1 (2089727..2090665, complement)

    Chromosome 1 - NC_012029.1Genomic Context describing neighboring genes Neighboring gene ABC transporter ATP-binding protein Neighboring gene ABC transporter ATP-binding protein Neighboring gene branched-chain amino acid ABC transporter permease Neighboring gene branched-chain amino acid ABC transporter permease Neighboring gene MATE family efflux transporter Neighboring gene cysteine hydrolase family protein Neighboring gene YqcI/YcgG family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_012029.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The lipoate synthase from Escherichia coli is an iron-sulfur protein. Ollagnier-de Choudens S, et al. FEBS Lett, 1999 Jun 18. PMID 10403368
    2. Isolation and characterization of LIP5. A lipoate biosynthetic locus of Saccharomyces cerevisiae. Sulo P, et al. J Biol Chem, 1993 Aug 15. PMID 8349643
    3. Complete genome sequence of the Antarctic Halorubrum lacusprofundi type strain ACAM 34. Anderson IJ, et al. Stand Genomic Sci, 2016. PMID 27617060, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    lipoyl synthase
    WP_015910799.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_012029.1 Reference assembly

      Range
      2089727..2090665 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_015910799.1 lipoyl synthase [Halorubrum lacusprofundi]

      See identical proteins and their annotated locations for WP_015910799.1

      UniProtKB/Swiss-Prot
      B9LR22
      Conserved Domains (3) summary
      cd01335
      Location:64 → 238
      Radical_SAM; Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster. ...
      PRK05481
      Location:1 → 291
      PRK05481; lipoyl synthase; Provisional
      pfam16881
      Location:6 → 42
      LIAS_N; N-terminal domain of lipoyl synthase of Radical_SAM family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B9LR22.1

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