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    INE75_RS17250 uroporphyrinogen-III synthase [ Bacteroides uniformis CL03T12C37 ]

    Gene ID: 66283615, updated on 3-Dec-2024

    Summary

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    Gene symbol
    INE75_RS17250
    Gene description
    uroporphyrinogen-III synthase
    Locus tag
    INE75_RS17250
    Gene type
    protein coding
    Organism
    Bacteroides uniformis CL03T12C37 (strain: CL03T12C37, nat-host: Homo sapiens)
    Lineage
    Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides
    Old locus tag
    INE75_03479
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    Genomic context

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    NZ_CP072255.1Genomic Context describing neighboring genes Neighboring gene TatD family hydrolase Neighboring gene membrane protein insertion efficiency factor YidD Neighboring gene ribonuclease P protein component Neighboring gene DUF4271 domain-containing protein Neighboring gene TIGR00730 family Rossman fold protein Neighboring gene RHS repeat-associated core domain-containing protein Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP072255.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural diversity in metal ion chelation and the structure of uroporphyrinogen III synthase. Schubert HL, et al. Biochem Soc Trans, 2002 Aug. PMID 12196144
    2. Mobile Type VI secretion system loci of the gut Bacteroidales display extensive intra-ecosystem transfer, multi-species spread and geographical clustering. García-Bayona L, et al. PLoS Genet, 2021 Apr. PMID 33901198, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    uroporphyrinogen-III synthase
    WP_005834069.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP072255.1 Reference assembly

      Range
      4111947..4112699 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_005834069.1 MULTISPECIES: uroporphyrinogen-III synthase [Bacteroides]

      See identical proteins and their annotated locations for WP_005834069.1

      UniProtKB/TrEMBL
      A0A078RX35, A0A139K5H1, A0A285S1A1, A0A3A5P7K3, A0A3A5QV84, A0A3A5RT28, A0A3A5RYP6, A0A3A5SFS0, A0A3A5WF62, A0A3A5WIM9, A0A3A5Y630, A0A3A5YXZ0, A0A3A5ZJB2, A0A3A6C0B0, A0A3A6K592, A0A4P6RGU0, A0A7D7BUG7, A0A8B3EE90, A0AAV3DGC3, E5V6S9
      Conserved Domains (1) summary
      cd06578
      Location:6 → 239
      HemD; Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in ...
    Nucleotide Protein
    Heading Accession and Version

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