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    MCAN_RS05900 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase [ Mycobacterium canettii CIPT 140010059 ]

    Gene ID: 45425080, updated on 11-Dec-2024

    Summary

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    Gene symbol
    MCAN_RS05900
    Gene description
    3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase
    Locus tag
    MCAN_RS05900
    Gene type
    protein coding
    Organism
    Mycobacterium canettii CIPT 140010059 (strain: CIPT 140010059)
    Lineage
    Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis complex
    Old locus tag
    MCAN_11161
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    Genomic context

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    Sequence:
    NC_015848.1 (1251012..1252124, complement)

    NC_015848.1Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene pseudo Neighboring gene type II toxin-antitoxin system antitoxin MazE3 Neighboring gene exodeoxyribonuclease VII small subunit Neighboring gene exodeoxyribonuclease VII large subunit Neighboring gene lipid droplet-associated protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_015848.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Rv1106c from Mycobacterium tuberculosis is a 3beta-hydroxysteroid dehydrogenase. Yang X, et al. Biochemistry, 2007 Aug 7. PMID 17630785, Free PMC Article
    2. Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis. Supply P, et al. Nat Genet, 2013 Feb. PMID 23291586, Free PMC Article
    3. The genome of Mycobacterium africanum West African 2 reveals a lineage-specific locus and genome erosion common to the M. tuberculosis complex. Bentley SD, et al. PLoS Negl Trop Dis, 2012. PMID 22389744, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    General protein information

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    Preferred Names
    3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_015848.1 Reference assembly

      Range
      1251012..1252124 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_003405840.1 MULTISPECIES: 3 beta-hydroxysteroid dehydrogenase/delta 5-->4-isomerase [Mycobacterium]

      See identical proteins and their annotated locations for WP_003405840.1

      UniProtKB/Swiss-Prot
      L0T7C3, O53454, P9WQP6, P9WQP7, Q7D8U6
      UniProtKB/TrEMBL
      A0A045K7Q6, A0A0H3M427, A0A1R3XXD8, A0A829C6K0, A0A9P2M3F7, A0AAU0QBI8, A0AAW8I449, A0AAX1PXZ2, A5U1F3, R4MBX8
      Conserved Domains (1) summary
      cd05241
      Location:16 → 348
      3b-HSD-like_SDR_e; 3beta-hydroxysteroid dehydrogenases (3b-HSD)-like, extended (e) SDRs
    Nucleotide Protein
    Heading Accession and Version

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