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    ermCL 23S rRNA methylase leader peptide ErmCL [ Streptococcus agalactiae ]

    Gene ID: 66886964, updated on 6-Jun-2024

    Summary

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    Gene symbol
    ermCL
    Gene description
    23S rRNA methylase leader peptide ErmCL
    Locus tag
    AMM49_RS11170
    Gene type
    protein coding
    Organism
    Streptococcus agalactiae (strain: NGBS128, nat-host: Homo sapiens)
    Lineage
    Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
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    Genomic context

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    Location:
    plasmid: pNGBS128

    NZ_CP012742.1Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene plasmid recombination protein Neighboring gene 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(T) Neighboring gene hypothetical protein Neighboring gene replication protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NZ_CP012742.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular characterization of Streptococcus agalactiae isolates harboring small erm(T)-carrying plasmids. Compain F, et al. Antimicrob Agents Chemother, 2014 Nov. PMID 25136004, Free PMC Article
    2. Drug sensing by the ribosome induces translational arrest via active site perturbation. Arenz S, et al. Mol Cell, 2014 Nov 6. PMID 25306253, Free PMC Article
    3. Critical 23S rRNA interactions for macrolide-dependent ribosome stalling on the ErmCL nascent peptide chain. Koch M, et al. Nucleic Acids Res, 2017 Jun 20. PMID 28369621, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General protein information

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    Preferred Names
    23S rRNA methylase leader peptide ErmCL

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NZ_CP012742.1 Reference assembly

      Range
      2509..2568
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      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. WP_002503927.1 MULTISPECIES: 23S rRNA methylase leader peptide ErmCL [Bacteria]

      See identical proteins and their annotated locations for WP_002503927.1

      UniProtKB/TrEMBL
      A0AAE7CVG5, A8W664, D7PTT4, G3ER40, K0KYZ0, L8BRR9, Q2YHL5, Q3KUQ6, Q57313, Q799A5, Q7AY86
      Conserved Domains (1) summary
      NF033690
      Location:1 → 19
      ErmCL_fam_lead; ErmCL family antibiotic resistance leader peptide
    Nucleotide Protein
    Heading Accession and Version