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    Xkr6 XK related 6 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 305960, updated on 9-Dec-2024

    Summary

    Official Symbol
    Xkr6provided by RGD
    Official Full Name
    XK related 6provided by RGD
    Primary source
    RGD:1310719
    See related
    EnsemblRapid:ENSRNOG00000011634 AllianceGenome:RGD:1310719
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    XRG6; RGD1310719
    Summary
    Predicted to be involved in apoptotic process involved in development; engulfment of apoptotic cell; and phosphatidylserine exposure on apoptotic cell surface. Predicted to be active in plasma membrane. Orthologous to human XKR6 (XK related 6). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Brain (RPKM 53.8), Adrenal (RPKM 13.0) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Xkr6 in Genome Data Viewer
    Location:
    15p12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (42032411..42269300)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (37857096..38059699)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (46784963..47173352)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene myotubularin related protein 9 Neighboring gene transfer RNA proline (anticodon AGG) 32 Neighboring gene uncharacterized LOC102548944 Neighboring gene uncharacterized LOC120097014 Neighboring gene microRNA 598 Neighboring gene uncharacterized LOC102553493 Neighboring gene uncharacterized LOC134482131 Neighboring gene PIN2/TERF1 interacting, telomerase inhibitor 1 Neighboring gene uncharacterized LOC102549097

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in apoptotic process involved in development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in engulfment of apoptotic cell IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in phosphatidylserine exposure on apoptotic cell surface IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    XK-related protein 6
    Names
    X Kell blood group precursor related family member 6 homolog
    X-linked Kx blood group related 6
    XK, Kell blood group complex subunit-related family, member 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001012042.1NP_001012042.1  XK-related protein 6

      See identical proteins and their annotated locations for NP_001012042.1

      Status: PROVISIONAL

      Source sequence(s)
      AY534260
      UniProtKB/Swiss-Prot
      Q5GH57
      UniProtKB/TrEMBL
      F1LPR0
      Related
      ENSRNOP00000015540.7, ENSRNOT00000015540.9
      Conserved Domains (1) summary
      pfam09815
      Location:131497
      XK-related; XK-related protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      42032411..42269300
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_010057819.1 RNA Sequence