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    TICAM1 toll like receptor adaptor molecule 1 [ Pteropus alecto (black flying fox) ]

    Gene ID: 102896235, updated on 30-Mar-2024

    Summary

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    Gene symbol
    TICAM1
    Gene description
    toll like receptor adaptor molecule 1
    Locus tag
    PAL_GLEAN10006079
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Pteropus alecto
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yinpterochiroptera; Pteropodoidea; Pteropodidae; Pteropodinae; Pteropus
    Orthologs
    human mouse all
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    Genomic context

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    See TICAM1 in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    102 current ASM32557v1 (GCF_000325575.1) Unplaced Scaffold NW_006429782.1 (2913606..2920034, complement)

    NW_006429782.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107195296 Neighboring gene fem-1 homolog A Neighboring gene uncharacterized LOC112475610 Neighboring gene perilipin 3 Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC102896741 Neighboring gene arrestin domain containing 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_006429782 Unplaced Scaffold Reference ASM32557v1 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative analysis of bat genomes provides insight into the evolution of flight and immunity. Zhang G, et al. Science, 2013 Jan 25. PMID 23258410, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein kinase binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in TRIF-dependent toll-like receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in lipopolysaccharide-mediated signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of NF-kappaB transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of cytokine production involved in inflammatory response IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of myeloid dendritic cell cytokine production IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in positive regulation of natural killer cell activation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in response to exogenous dsRNA IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    TIR domain-containing adapter molecule 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Pteropus alecto Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference ASM32557v1 Primary Assembly

    Genomic

    1. NW_006429782.1 Reference ASM32557v1 Primary Assembly

      Range
      2913606..2920034 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006904118.3 → XP_006904180.1  TIR domain-containing adapter molecule 1

      See identical proteins and their annotated locations for XP_006904180.1

      UniProtKB/TrEMBL
      L5L7P2
      Conserved Domains (1) summary
      pfam12721
      Location:649 → 678
      RHIM; RIP homotypic interaction motif
    Nucleotide Protein
    Heading Accession and Version

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