AlaAT1 alanine aminotransferas [Arabidopsis thaliana (thale cress)] - Gene

Summary

Official Symbol: AlaAT1
Official Full Name: alanine aminotransferas
Primary source: TAIR:AT1G17290
Locus tag: AT1G17290
See related: Araport:AT1G17290
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: alanine aminotransferas; ALANINE AMINOTRANSFERAS; T13M22.3; T13M22_3
Summary: Encodes for alanine aminotransferase (ALAAT1), involved in alanine catabolism during plants recovery from hypoxia
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Chromosome 1 - NC_003070.9 Genomic Context describing neighboring genes

Go to nucleotide: Graphics FASTA GenBank

ALAAT1 and ALAAT2 link mitochondrial glycolate oxidation to the major photorespiratory pathway.
Title: Two alanine aminotranferases link mitochondrial glycolate oxidation to the major photorespiratory pathway in Arabidopsis and rice.

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

NM_101591.6

Function	Evidence Code	Pubs
enables ATP binding	HDA more info	PubMed
enables L-alanine:2-oxoglutarate aminotransferase activity	IDA Inferred from Direct Assay more info	PubMed
enables pyridoxal phosphate binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within L-alanine catabolic process, by transamination	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in biosynthetic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cellular response to hypoxia	HEP more info	PubMed
acts_upstream_of_or_within response to cadmium ion	IEP Inferred from Expression Pattern more info	PubMed
acts_upstream_of_or_within response to hypoxia	IEP Inferred from Expression Pattern more info	PubMed

Component	Evidence Code	Pubs
NOT located_in cytosol	RCA inferred from Reviewed Computational Analysis more info	PubMed
located_in mitochondrion	HDA more info	PubMed
located_in mitochondrion	ISM Inferred from Sequence Model more info
located_in nucleus	HDA more info	PubMed

NP_173173.3

alanine aminotransferas (AlaAT1); FUNCTIONS IN: L-alanine:2-oxoglutarate aminotransferase activity, ATP binding; INVOLVED IN: response to cadmium ion, response to hypoxia, L-alanine catabolic process, by transamination; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 9 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage; CONTAINS InterPro DOMAIN/s: 1-aminocyclopropane-1-carboxylate synthase (InterPro:IPR001176), Pyridoxal phosphate-dependent transferase, major domain (InterPro:IPR015424), Aminotransferase, class I/classII (InterPro:IPR004839), Pyridoxal phosphate-dependent transferase, major region, subdomain 2 (InterPro:IPR015422), Pyridoxal phosphate-dependent transferase, major region, subdomain 1 (InterPro:IPR015421); BEST Arabidopsis thaliana protein match is: alanine aminotransferase 2 (TAIR:AT1G72330.1); Has 28241 Blast hits to 28232 proteins in 2888 species: Archae - 752; Bacteria - 19527; Metazoa - 637; Fungi - 692; Plants - 1303; Viruses - 0; Other Eukaryotes - 5330 (source: NCBI BLink).