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    PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha [ Desmodus rotundus (common vampire bat) ]

    Gene ID: 112307667, updated on 30-Mar-2024

    Summary

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    Gene symbol
    PIK3CA
    Gene description
    phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Desmodus rotundus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Phyllostomidae; Desmodontinae; Desmodus
    Orthologs
    human mouse all
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    Genomic context

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    See PIK3CA in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    RS_2023_02 current HLdesRot8A (GCF_022682495.1) 2 NC_071388.1 (39047935..39129328)
    101 previous assembly ASM294091v2 (GCF_002940915.1) Unplaced Scaffold NW_020090470.1 (39900177..39958836)

    Chromosome 2 - NC_071388.1Genomic Context describing neighboring genes Neighboring gene zinc finger matrin-type 3 Neighboring gene U6 spliceosomal RNA Neighboring gene translation initiation factor IF-2-like Neighboring gene U6 spliceosomal RNA Neighboring gene potassium calcium-activated channel subfamily M regulatory beta subunit 3 Neighboring gene zinc finger protein 639

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in phosphatidylinositol-mediated signaling IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class IA IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of phosphatidylinositol 3-kinase complex, class IB IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
    Names
    Putative phosphatidylinositol 3-kinase vps34 involved in signal transduction

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_022682495.1-RS_2023_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference HLdesRot8A Primary Assembly

    Genomic

    1. NC_071388.1 Reference HLdesRot8A Primary Assembly

      Range
      39047935..39129328
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_053918106.1 → XP_053774081.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1

      UniProtKB/TrEMBL
      K9IPS4

    2. XM_053918105.1 → XP_053774080.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1

      UniProtKB/TrEMBL
      K9IPS4

    3. XM_053918109.1 → XP_053774084.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X2

    4. XM_053918108.1 → XP_053774083.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1

      UniProtKB/TrEMBL
      K9IPS4

    5. XM_053918107.1 → XP_053774082.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform isoform X1

      UniProtKB/TrEMBL
      K9IPS4
    Nucleotide Protein
    Heading Accession and Version

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