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    zgc:64051 zgc:64051 [ Danio rerio (zebrafish) ]

    Gene ID: 393342, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zgc:64051provided by ZNC
    Official Full Name
    zgc:64051provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1349
    See related
    Ensembl:ENSDARG00000068233 AllianceGenome:ZFIN:ZDB-GENE-040426-1349
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Summary
    Predicted to be located in membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including anterior axial hypoblast; blood; mesoderm; tail bud; and vasculature. Orthologous to human CD53 (CD53 molecule). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See zgc:64051 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (26869580..26879302, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (26269427..26279149, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene IMP U3 small nucleolar ribonucleoprotein 4 Neighboring gene A-Raf proto-oncogene, serine/threonine kinase Neighboring gene lectin, mannose-binding 2-like b Neighboring gene uncharacterized LOC137495515

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Macrophage-specific gene functions in Spi1-directed innate immunity. Zakrzewska A, et al. Blood, 2010 Jul 22. PMID 20424185
    2. Identification of a conserved and acute neurodegeneration-specific microglial transcriptome in the zebrafish. Oosterhof N, et al. Glia, 2017 Jan. PMID 27757989, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC64051

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    leukocyte surface antigen CD53

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200371.1 → NP_956665.1  leukocyte surface antigen CD53

      See identical proteins and their annotated locations for NP_956665.1

      Status: PREDICTED

      Source sequence(s)
      BC053225
      UniProtKB/TrEMBL
      B2GRA1, F6P0Q6, Q7T376
      Related
      ENSDARP00000089342.4, ENSDART00000098571.6
      Conserved Domains (2) summary
      cd03164
      Location:101 → 189
      CD53_like_LEL; Tetraspanin, extracellular domain or large extracellular loop (LEL), CD53_Like family. Tetraspanins are trans-membrane proteins with 4 trans-membrane segments. Both the N- and C-termini lie on the intracellular side of the membrane. This alignment model ...
      pfam00335
      Location:6 → 213
      Tetraspannin; Tetraspanin family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      26869580..26879302 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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