sh3bgrl3 SH3 domain binding glutamate-rich protein like 3 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sh3bgrl3provided by ZNC
Official Full Name: SH3 domain binding glutamate-rich protein like 3provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1059
See related: Ensembl:ENSDARG00000098075 AllianceGenome:ZFIN:ZDB-GENE-040426-1059
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:56517; si:dkey-194c21.3
Summary: Predicted to be located in nucleus and ruffle membrane. Predicted to be active in cytoplasm. Is expressed in central nervous system; digestive system; notochord; otic vesicle; and sensory system. Orthologous to human SH3BGRL3 (SH3 domain binding glutamate rich protein like 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 19

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (13939750..13950232, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (14077555..14088037, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in ruffle membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: SH3 domain-binding glutamic acid-rich-like protein 3

Names: SH3 domain binding glutamic acid-rich protein like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200278.2 → NP_956572.1 SH3 domain-binding glutamic acid-rich-like protein 3

See identical proteins and their annotated locations for NP_956572.1

Status: VALIDATED

Source sequence(s)

BX530067, EH440040

UniProtKB/TrEMBL

A0A8N1Z2Z4, Q7ZUC9

Related

ENSDARP00000131054.1, ENSDART00000168665.2

Conserved Domains (1) summary

cd03030
Location:2 → 91

GRX_SH3BGR; Glutaredoxin (GRX) family, SH3BGR (SH3 domain binding glutamic acid-rich protein) subfamily; a recently-identified subfamily composed of SH3BGR and similar proteins possessing significant sequence similarity to GRX, but without a redox active CXXC motif. ...