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    • Showing Current items.

    rsks-1 Ribosomal protein S6 kinase beta [ Caenorhabditis elegans ]

    Gene ID: 176554, updated on 9-Dec-2024

    Summary

    Official Symbol
    rsks-1
    Official Full Name
    Ribosomal protein S6 kinase beta
    Primary source
    WormBase:WBGene00012929
    Locus tag
    CELE_Y47D3A.16
    See related
    AllianceGenome:WB:WBGene00012929
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein serine/threonine kinase activity. Involved in several processes, including determination of adult lifespan; nematode larval development; and positive regulation of autophagosome assembly. Predicted to be located in axon and perikaryon. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in several structures, including Eal; Eala; Ealaa; Ealp; and Ear. Orthologous to several human genes including RPS6KB2 (ribosomal protein S6 kinase B2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See rsks-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (11245120..11252281)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene CMP/dCMP-type deaminase domain-containing protein Neighboring gene ncRNA Neighboring gene Association with the SNF1 complex (ASC) domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Oxysterol-binding protein

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in TORC1 signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in determination of adult lifespan IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    NOT involved_in determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in nematode larval development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in positive regulation of autophagosome assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in perikaryon IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Ribosomal protein S6 kinase beta
    NP_499447.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      11245120..11252281
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067046.4NP_499447.2  Ribosomal protein S6 kinase beta [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499447.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9NAH6
      Conserved Domains (2) summary
      smart00220
      Location:83344
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05584
      Location:86408
      STKc_p70S6K; Catalytic domain of the Serine/Threonine Kinase, 70 kDa ribosomal protein S6 kinase