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    eas easily shocked [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32585, updated on 17-Dec-2024

    Summary

    Official Symbol
    easprovided by FlyBase
    Official Full Name
    easily shockedprovided by FlyBase
    Primary source
    FLYBASE:FBgn0000536
    Locus tag
    Dmel_CG3525
    See related
    AllianceGenome:FB:FBgn0000536
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    ala; CG3525; Dmel\CG3525; EP770; EtnK; PC80; RE10142; RH11
    Summary
    Enables ethanolamine kinase activity. Involved in several processes, including mechanosensory behavior; nervous system development; and phosphatidylethanolamine metabolic process. Predicted to be active in cytoplasm. Used to study epilepsy and heart conduction disease. Orthologous to several human genes including ETNK1 (ethanolamine kinase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See eas in Genome Data Viewer
    Location:
    14B7-14B7; 1-53 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (16278328..16285618)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (16172361..16179651)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene katanin 80 Neighboring gene peroxisomal Multifunctional enzyme type 2 Neighboring gene Proteasome alpha4 subunit Neighboring gene uncharacterized protein Neighboring gene Ubiquinol-cytochrome c reductase 14 kDa subunit Neighboring gene cabeza

    Genomic regions, transcripts, and products

    Bibliography

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables choline kinase activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables ethanolamine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ethanolamine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    easily shocked
    Names
    CG3525-PA
    CG3525-PB
    CG3525-PC
    CG3525-PF
    CG3525-PG
    CG3525-PH
    CG3525-PI
    CG3525-PJ
    alpha lobes absent
    alpha-lobe absent
    eas-PA
    eas-PB
    eas-PC
    eas-PF
    eas-PG
    eas-PH
    eas-PI
    eas-PJ
    easily-shocked
    ethanolamine kinase
    NP_001245706.1
    NP_001245707.1
    NP_001285319.1
    NP_523364.2
    NP_727941.2
    NP_727942.1
    NP_727943.1
    NP_788914.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      16278328..16285618
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258777.1NP_001245706.1  easily shocked, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245706.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JFQ7
    2. NM_001298390.1NP_001285319.1  easily shocked, isoform J [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285319.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      X2JFQ7
    3. NM_167489.2NP_727941.2  easily shocked, isoform I [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727941.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C8VV66, M9NEJ9, M9NGH8, P54352, Q1RL01, Q540Y9, Q86B51, Q8IR20, Q9VXI7
      Conserved Domains (1) summary
      cd05157
      Location:126478
      ETNK_euk; Euykaryotic Ethanolamine kinase
    4. NM_001258778.2NP_001245707.1  easily shocked, isoform G [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245707.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P54352
    5. NM_167490.3NP_727942.1  easily shocked, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727942.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C8VV66, M9NEJ9, M9NGH8, P54352, Q1RL01, Q540Y9, Q86B51, Q8IR20, Q9VXI7
      Related
      FBpp0073990
      Conserved Domains (1) summary
      cd05157
      Location:126478
      ETNK_euk; Euykaryotic Ethanolamine kinase
    6. NM_176741.3NP_788914.2  easily shocked, isoform H [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788914.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C8VV66, M9NEJ9, M9NGH8, P54352, Q1RL01, Q540Y9, Q86B51, Q8IR20, Q9VXI7
      Conserved Domains (1) summary
      cd05157
      Location:126478
      ETNK_euk; Euykaryotic Ethanolamine kinase
    7. NM_078640.4NP_523364.2  easily shocked, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523364.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C8VV66, M9NEJ9, M9NGH8, P54352, Q1RL01, Q540Y9, Q86B51, Q8IR20, Q9VXI7
      Related
      FBpp0073991
      Conserved Domains (1) summary
      cd05157
      Location:126478
      ETNK_euk; Euykaryotic Ethanolamine kinase
    8. NM_167491.2NP_727943.1  easily shocked, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_727943.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      C8VV66, M9NEJ9, M9NGH8, P54352, Q1RL01, Q540Y9, Q86B51, Q8IR20, Q9VXI7
      Related
      FBpp0073993
      Conserved Domains (1) summary
      cd05157
      Location:126478
      ETNK_euk; Euykaryotic Ethanolamine kinase