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    DKK1 dickkopf WNT signaling pathway inhibitor 1 [ Pan troglodytes (chimpanzee) ]

    Gene ID: 450465, updated on 17-Aug-2024

    Summary

    Official Symbol
    DKK1provided by VGNC
    Official Full Name
    dickkopf WNT signaling pathway inhibitor 1provided by VGNC
    Primary source
    VGNC:VGNC:1625
    Locus tag
    CK820_G0008135
    See related
    Ensembl:ENSPTRG00000002511
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pan troglodytes
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Pan
    Orthologs
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    Genomic context

    See DKK1 in Genome Data Viewer
    Location:
    chromosome: 8
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current NHGRI_mPanTro3-v2.0_pri (GCF_028858775.2) 8 NC_072406.2 (64700726..64704114)
    RS_2023_04 previous assembly NHGRI_mPanTro3-v1.1-hic.freeze_pri (GCF_028858775.1) 10 NC_072408.1 (55310849..55314237)

    Chromosome 8 - NC_072406.2Genomic Context describing neighboring genes Neighboring gene protein kinase cGMP-dependent 1 Neighboring gene uncharacterized LOC129136189 Neighboring gene uncharacterized LOC112204590 Neighboring gene large ribosomal subunit protein eL31-like Neighboring gene 52 kDa repressor of the inhibitor of the protein kinase-like

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables co-receptor binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables receptor antagonist activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in negative regulation of canonical Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in extracellular space IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    dickkopf-related protein 1
    Names
    dickkopf 1 homolog
    dickkopf homolog 1
    dickkopf-like protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001261842.2NP_001248771.1  dickkopf-related protein 1 precursor

      See identical proteins and their annotated locations for NP_001248771.1

      Status: PROVISIONAL

      Source sequence(s)
      JN966745
      UniProtKB/TrEMBL
      A0A2J8NVN7, A0A8I3B2I1, H2Q1X1, I1W661, K7BC16
      Related
      ENSPTRP00000004327.4, ENSPTRT00000004697.4
      Conserved Domains (1) summary
      pfam04706
      Location:85139
      Dickkopf_N; Dickkopf N-terminal cysteine-rich region

    RefSeqs of Annotated Genomes: GCF_028858775.2-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

    Genomic

    1. NC_072406.2 Reference NHGRI_mPanTro3-v2.0_pri Primary Assembly

      Range
      64700726..64704114
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)