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    LAMA4 laminin subunit alpha 4 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 696685, updated on 17-Aug-2024

    Summary

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    Official Symbol
    LAMA4provided by VGNC
    Official Full Name
    laminin subunit alpha 4provided by VGNC
    Primary source
    VGNC:VGNC:74227
    See related
    Ensembl:ENSMMUG00000013782
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See LAMA4 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    40
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (15744055..15892395, complement)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (155700716..155851171)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene tubulin epsilon 1 Neighboring gene family with sequence similarity 229 member B Neighboring gene U6 spliceosomal RNA Neighboring gene PIN2/TERF1-interacting telomerase inhibitor 1-like Neighboring gene ret finger protein like 4B

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables signaling receptor binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell migration IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of embryonic development IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    laminin subunit alpha-4
    Names
    laminin, alpha 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      15744055..15892395 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_028847051.1 → XP_028702884.1  laminin subunit alpha-4 isoform X1

      UniProtKB/TrEMBL
      G7MQQ2
      Related
      ENSMMUP00000079379.1, ENSMMUT00000086660.1
      Conserved Domains (6) summary
      smart00282
      Location:860 → 1013
      LamG; Laminin G domain
      COG1196
      Location:407 → 752
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00055
      Location:187 → 238
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:1492 → 1624
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam06009
      Location:734 → 861
      Laminin_II; Laminin Domain II
      pfam06008
      Location:298 → 554
      Laminin_I; Laminin Domain I

    2. XM_015137555.2 → XP_014993041.2  laminin subunit alpha-4 isoform X1

      UniProtKB/TrEMBL
      G7MQQ2
      Conserved Domains (6) summary
      smart00282
      Location:860 → 1013
      LamG; Laminin G domain
      COG1196
      Location:407 → 752
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00055
      Location:187 → 238
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:1492 → 1624
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam06009
      Location:734 → 861
      Laminin_II; Laminin Domain II
      pfam06008
      Location:298 → 554
      Laminin_I; Laminin Domain I

    3. XM_015137556.2 → XP_014993042.2  laminin subunit alpha-4 isoform X2

      UniProtKB/TrEMBL
      F6PZI2, I2CVN4
      Related
      ENSMMUP00000018124.4, ENSMMUT00000019353.4
      Conserved Domains (6) summary
      smart00282
      Location:853 → 1006
      LamG; Laminin G domain
      COG1196
      Location:400 → 745
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      cd00055
      Location:187 → 238
      EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
      cd00110
      Location:1485 → 1617
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
      pfam06009
      Location:727 → 854
      Laminin_II; Laminin Domain II
      pfam06008
      Location:291 → 547
      Laminin_I; Laminin Domain I
    Nucleotide Protein
    Heading Accession and Version

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