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    RAD50 RAD50 double strand break repair protein [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 710718, updated on 5-Mar-2024

    Summary

    Gene symbol
    RAD50
    Gene description
    RAD50 double strand break repair protein
    See related
    Ensembl:ENSMMUG00000003130
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
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    Genomic context

    See RAD50 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 6 NC_041759.1 (129998030..130086397)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 6 NC_027898.1 (130239775..130330792)

    Chromosome 6 - NC_041759.1Genomic Context describing neighboring genes Neighboring gene colitis associated IRF1 antisense regulator of intestinal homeostasis Neighboring gene interferon regulatory factor 1 Neighboring gene interleukin 5 Neighboring gene uncharacterized LOC114678902 Neighboring gene uncharacterized LOC114678713 Neighboring gene interleukin 13

    Genomic regions, transcripts, and products

    General gene information

    Markers

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables G-quadruplex DNA binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables double-stranded telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    enables single-stranded telomeric DNA binding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in DNA duplex unwinding IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in chromosome organization involved in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in double-strand break repair IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in telomere maintenance via recombination IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    involved_in telomere maintenance via telomerase IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of Mre11 complex IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in condensed nuclear chromosome IEA
    Inferred from Electronic Annotation
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    PubMed 

    General protein information

    Preferred Names
    DNA repair protein RAD50
    Names
    RAD50 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041759.1 Reference Mmul_10 Primary Assembly

      Range
      129998030..130086397
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015140734.2XP_014996220.1  DNA repair protein RAD50 isoform X1

      UniProtKB/TrEMBL
      F7DGI4, H9YVE3
      Related
      ENSMMUP00000004184.3, ENSMMUT00000004435.4
      Conserved Domains (4) summary
      TIGR00606
      Location:21323
      rad50; rad50
      cd03240
      Location:12061308
      ABC_Rad50; ATP-binding cassette domain of Rad50
      pfam00901
      Location:720973
      Orbi_VP5; Orbivirus outer capsid protein VP5
      pfam04423
      Location:670720
      Rad50_zn_hook; Rad50 zinc hook motif
    2. XM_015140735.2XP_014996221.1  DNA repair protein RAD50 isoform X1

      UniProtKB/TrEMBL
      F7DGI4, H9YVE3
      Conserved Domains (4) summary
      TIGR00606
      Location:21323
      rad50; rad50
      cd03240
      Location:12061308
      ABC_Rad50; ATP-binding cassette domain of Rad50
      pfam00901
      Location:720973
      Orbi_VP5; Orbivirus outer capsid protein VP5
      pfam04423
      Location:670720
      Rad50_zn_hook; Rad50 zinc hook motif
    3. XM_015140736.2XP_014996222.1  DNA repair protein RAD50 isoform X2

      UniProtKB/TrEMBL
      H9FNF3, H9YVE3
      Related
      ENSMMUP00000053030.2, ENSMMUT00000068023.2
      Conserved Domains (1) summary
      TIGR00606
      Location:21312
      rad50
    4. XM_015140739.2XP_014996225.1  DNA repair protein RAD50 isoform X6

      UniProtKB/TrEMBL
      A0A1D5QN14
      Conserved Domains (1) summary
      TIGR00606
      Location:11173
      rad50
    5. XM_015140737.2XP_014996223.1  DNA repair protein RAD50 isoform X3

      UniProtKB/TrEMBL
      A0A1D5QN14
      Conserved Domains (4) summary
      TIGR00606
      Location:381289
      rad50; rad50
      cd03240
      Location:11721274
      ABC_Rad50; ATP-binding cassette domain of Rad50
      pfam04423
      Location:636686
      Rad50_zn_hook; Rad50 zinc hook motif
      cl21455
      Location:37132
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
    6. XM_028849711.1XP_028705544.1  DNA repair protein RAD50 isoform X4

      UniProtKB/TrEMBL
      A0A1D5QN14
      Conserved Domains (1) summary
      TIGR00606
      Location:11224
      rad50
    7. XM_015140738.2XP_014996224.1  DNA repair protein RAD50 isoform X5

      UniProtKB/TrEMBL
      A0A1D5QN14
      Conserved Domains (4) summary
      TIGR00606
      Location:11184
      rad50; rad50
      cd03240
      Location:10671169
      ABC_Rad50; ATP-binding cassette domain of Rad50
      pfam04423
      Location:531581
      Rad50_zn_hook; Rad50 zinc hook motif
      cl21455
      Location:1027
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases