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    RNF146 ring finger protein 146 [ Macaca mulatta (Rhesus monkey) ]

    Gene ID: 712152, updated on 17-Aug-2024

    Summary

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    Official Symbol
    RNF146provided by VGNC
    Official Full Name
    ring finger protein 146provided by VGNC
    Primary source
    VGNC:VGNC:76798
    Locus tag
    EGK_15370
    See related
    Ensembl:ENSMMUG00000015354
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Macaca mulatta
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
    Orthologs
    human mouse all
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    Genomic context

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    See RNF146 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    103 current Mmul_10 (GCF_003339765.1) 4 NC_041757.1 (30808474..30830192)
    102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 4 NC_027896.1 (140329920..140351828, complement)

    Chromosome 4 - NC_041757.1Genomic Context describing neighboring genes Neighboring gene R-spondin 3 Neighboring gene uncharacterized LOC106998157 Neighboring gene uncharacterized LOC114677484 Neighboring gene ethylmalonyl-CoA decarboxylase 1 Neighboring gene 14-3-3 protein zeta/delta pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
    2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
    3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables poly-ADP-D-ribose binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables ubiquitin protein ligase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF146
    NP_001253516.1
    XP_014992779.1
    XP_014992780.1
    XP_014992782.1
    XP_014992783.1
    XP_014992784.1
    XP_028702624.1
    XP_028702625.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001266587.1 → NP_001253516.1  E3 ubiquitin-protein ligase RNF146

      See identical proteins and their annotated locations for NP_001253516.1

      Status: PROVISIONAL

      Source sequence(s)
      JV048356
      UniProtKB/TrEMBL
      A0A8J8XK00, F7GUD1, G7MQF3
      Conserved Domains (2) summary
      smart00678
      Location:103 → 175
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd16546
      Location:35 → 74
      RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

    RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Mmul_10 Primary Assembly

    Genomic

    1. NC_041757.1 Reference Mmul_10 Primary Assembly

      Range
      30808474..30830192
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_015137298.2 → XP_014992784.1  E3 ubiquitin-protein ligase RNF146 isoform X2

      UniProtKB/TrEMBL
      A0A8J8XK00, F7GUD1, G7MQF3
      Related
      ENSMMUP00000079705.1, ENSMMUT00000096822.1
      Conserved Domains (2) summary
      smart00678
      Location:103 → 175
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd16546
      Location:35 → 74
      RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

    2. XM_015137296.2 → XP_014992782.1  E3 ubiquitin-protein ligase RNF146 isoform X2

      UniProtKB/TrEMBL
      A0A8J8XK00, F7GUD1, G7MQF3
      Related
      ENSMMUP00000033088.1, ENSMMUT00000040018.3
      Conserved Domains (2) summary
      smart00678
      Location:103 → 175
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd16546
      Location:35 → 74
      RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

    3. XM_015137293.2 → XP_014992779.1  E3 ubiquitin-protein ligase RNF146 isoform X1

      UniProtKB/TrEMBL
      F6SP59
      Related
      ENSMMUP00000081157.1, ENSMMUT00000083246.1
      Conserved Domains (2) summary
      smart00678
      Location:104 → 176
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd16546
      Location:36 → 75
      RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

    4. XM_015137297.2 → XP_014992783.1  E3 ubiquitin-protein ligase RNF146 isoform X2

      UniProtKB/TrEMBL
      A0A8J8XK00, F7GUD1, G7MQF3
      Related
      ENSMMUP00000068244.1, ENSMMUT00000105506.1
      Conserved Domains (2) summary
      smart00678
      Location:103 → 175
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd16546
      Location:35 → 74
      RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

    5. XM_028846791.1 → XP_028702624.1  E3 ubiquitin-protein ligase RNF146 isoform X2

      UniProtKB/TrEMBL
      A0A8J8XK00, F7GUD1, G7MQF3
      Conserved Domains (2) summary
      smart00678
      Location:103 → 175
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd16546
      Location:35 → 74
      RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

    6. XM_015137294.2 → XP_014992780.1  E3 ubiquitin-protein ligase RNF146 isoform X1

      UniProtKB/TrEMBL
      F6SP59
      Related
      ENSMMUP00000020131.1, ENSMMUT00000021523.3
      Conserved Domains (2) summary
      smart00678
      Location:104 → 176
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd16546
      Location:36 → 75
      RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins

    7. XM_028846792.1 → XP_028702625.1  E3 ubiquitin-protein ligase RNF146 isoform X2

      UniProtKB/TrEMBL
      A0A8J8XK00, F7GUD1, G7MQF3
      Conserved Domains (2) summary
      smart00678
      Location:103 → 175
      WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
      cd16546
      Location:35 → 74
      RING-HC_RNF146; RING finger, HC subclass, found in RING finger protein 146 (RNF146) and similar proteins
    Nucleotide Protein
    Heading Accession and Version

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