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    drg2 developmentally regulated GTP binding protein 2 [ Danio rerio (zebrafish) ]

    Gene ID: 323355, updated on 9-Dec-2024

    Summary

    Official Symbol
    drg2provided by ZNC
    Official Full Name
    developmentally regulated GTP binding protein 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040808-29
    See related
    Ensembl:ENSDARG00000006642 AllianceGenome:ZFIN:ZDB-GENE-040808-29
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb96a09; wu:fb96b01; zgc:101029
    Summary
    Predicted to enable GTP binding activity. Predicted to be involved in cytoplasmic translation. Predicted to be active in cytoplasm. Orthologous to human DRG2 (developmentally regulated GTP binding protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See drg2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (40153819..40162867, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (40011961..40021009, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene LLGL scribble cell polarity complex component 1 Neighboring gene myosin XVAa Neighboring gene synaptogyrin 3a Neighboring gene growth factor, augmenter of liver regeneration (ERV1 homolog, S. cerevisiae)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC101029

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    developmentally-regulated GTP-binding protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212638.1NP_997803.1  developmentally-regulated GTP-binding protein 2

      See identical proteins and their annotated locations for NP_997803.1

      Status: PROVISIONAL

      Source sequence(s)
      AY398336
      UniProtKB/TrEMBL
      Q6AXJ4, Q6TH20
      Related
      ENSDARP00000008399.5, ENSDART00000025285.7
      Conserved Domains (4) summary
      cd01666
      Location:289363
      TGS_DRG_C; TGS_DRG_C: DRG (developmentally regulated GTP-binding protein) represents a family of GTP-binding proteins that includes two members, DRG1 and DRG2. DRG1 and DRG2 have a C-terminal TGS domain (named after the ThrRS, GTPase, and SpoT proteins where it ...
      cd01896
      Location:63295
      DRG; Developmentally Regulated GTP-binding protein (DRG)
      COG1163
      Location:1364
      Rbg1; Ribosome-interacting GTPase 1 [Translation, ribosomal structure and biogenesis]
      cl21455
      Location:3119
      P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      40153819..40162867 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)