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    Gch1 GTP cyclohydrolase 1 [ Cricetulus griseus (Chinese hamster) ]

    Gene ID: 100750667, updated on 8-Mar-2024

    Summary

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    Gene symbol
    Gch1
    Gene description
    GTP cyclohydrolase 1
    See related
    Ensembl:ENSCGRG00015000012
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cricetulus griseus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Cricetinae; Cricetulus
    Orthologs
    human mouse all
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    Genomic context

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    See Gch1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    104 current CriGri_1.0 (GCF_000223135.1) Unplaced Scaffold NW_003613770.1 (645262..676587)
    104 current CriGri-PICRH-1.0 (GCF_003668045.3) 1 Unlocalized Scaffold NW_023276807.1 (203179957..203211577, complement)

    NW_003613770.1Genomic Context describing neighboring genes Neighboring gene suppressor of cytokine signaling 4 Neighboring gene WD repeat and HMG-box DNA binding protein 1 Neighboring gene sterile alpha motif domain containing 4A Neighboring gene uncharacterized LOC103161390 Neighboring gene cell growth regulator with ring finger domain 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unraveling the Chinese hamster ovary cell line transcriptome by next-generation sequencing. Becker J, et al. J Biotechnol, 2011 Dec 10. PMID 21945585
    2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables GTP cyclohydrolase I activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in tetrahydrobiopterin biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in tetrahydrofolate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    GTP cyclohydrolase 1
    Names
    GTP cyclohydrolase 1-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cricetulus griseus Annotation Release 104 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference CriGri_1.0 Primary Assembly

    Genomic

    1. NW_003613770.1 Reference CriGri_1.0 Primary Assembly

      Range
      645262..676587
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_003500048.5 → XP_003500096.1  GTP cyclohydrolase 1

      See identical proteins and their annotated locations for XP_003500096.1

      UniProtKB/TrEMBL
      A0A8C2QIW5, G3H7B8
      Conserved Domains (1) summary
      cd00642
      Location:64 → 248
      GTP_cyclohydro1; GTP cyclohydrolase I (GTP-CH-I) catalyzes the conversion of GTP into dihydroneopterin triphosphate. The enzyme product is the precursor of tetrahydrofolate in eubacteria, fungi, and plants and of the folate analogs in methanogenic bacteria. In ...

    Alternate CriGri-PICRH-1.0

    Genomic

    1. NW_023276807.1 Alternate CriGri-PICRH-1.0

      Range
      203179957..203211577 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_027386540.2 → XP_027242341.1  GTP cyclohydrolase 1

      UniProtKB/TrEMBL
      A0A8C2QIW5, G3H7B8
      Related
      ENSCGRP00015046167.1, ENSCGRT00015065524.1
    Nucleotide Protein Strain
    Heading Accession and Version

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