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    skpo-3 ShKT domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 174191, updated on 9-Dec-2024

    Summary

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    Official Symbol
    skpo-3
    Official Full Name
    ShKT domain-containing protein
    Primary source
    WormBase:WBGene00017968
    Locus tag
    CELE_F32A5.2
    See related
    AllianceGenome:WB:WBGene00017968
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable peroxidase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See skpo-3 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    13
    Sequence:
    Chromosome: II; NC_003280.10 (7245876..7250181)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serine carboxypeptidase ctsa-3.1 Neighboring gene Aquaporin Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Peroxisomal membrane protein PEX13 Neighboring gene putative U6 snRNA-associated Sm-like protein LSm4 Neighboring gene SANT domain-containing protein Neighboring gene DeHydrogenases, Short chain

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcriptomics of ivermectin response in Caenorhabditis elegans: Integrating abamectin quantitative trait loci and comparison to the Ivermectin-exposed DA1316 strain. Dube F, et al. PLoS One, 2023. PMID 37141255, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peroxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular oxidant detoxification IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    ShKT domain-containing protein
    NP_495511.1
    • Confirmed by transcript evidence
    NP_495512.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7245876..7250181
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063110.5 → NP_495511.1  ShKT domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495511.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2KZ53
      Conserved Domains (2) summary
      smart00254
      Location:41 → 75
      ShKT; ShK toxin domain
      pfam03098
      Location:464 → 978
      An_peroxidase; Animal haem peroxidase

    2. NM_063111.5 → NP_495512.1  ShKT domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495512.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95QH5
      Conserved Domains (2) summary
      smart00254
      Location:41 → 75
      ShKT; ShK toxin domain
      pfam03098
      Location:323 → 837
      An_peroxidase; Animal haem peroxidase
    Nucleotide Protein
    Heading Accession and Version

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