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    Map10 microtubule-associated protein 10 [ Mus musculus (house mouse) ]

    Gene ID: 74393, updated on 9-Dec-2024

    Summary

    Official Symbol
    Map10provided by MGI
    Official Full Name
    microtubule-associated protein 10provided by MGI
    Primary source
    MGI:MGI:1921643
    See related
    Ensembl:ENSMUSG00000050930 AllianceGenome:MGI:1921643
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA1383; 4933403G14Rik
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in microtubule cytoskeleton organization; positive regulation of cytokinesis; and regulation of microtubule-based process. Predicted to be active in microtubule cytoskeleton and midbody. Orthologous to human MAP10 (microtubule associated protein 10). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See Map10 in Genome Data Viewer
    Location:
    8 E2; 8 73.65 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (126396557..126400104)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (125669818..125673365)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930567H12 gene Neighboring gene STARR-seq mESC enhancer starr_23041 Neighboring gene STARR-seq mESC enhancer starr_23042 Neighboring gene predicted gene, 30871 Neighboring gene STARR-positive B cell enhancer mm9_chr8:128195414-128195715 Neighboring gene predicted gene, 39282 Neighboring gene STARR-seq mESC enhancer starr_23044 Neighboring gene predicted gene, 39283

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Clone Names

    • KIAA1383

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables microtubule binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cytoplasmic microtubule organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cytoplasmic microtubule organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in mitotic spindle midzone assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitotic spindle midzone assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitotic spindle midzone assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cytokinesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of microtubule-based process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of microtubule-based process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in centrosome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in cytoplasmic microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic microtubule ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in midbody IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in midbody ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in mitotic spindle midzone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitotic spindle midzone ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle midzone ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in mitotic spindle pole IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitotic spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle pole ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    microtubule-associated protein 10
    Names
    microtubule regulator of 120 KDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028908.3NP_083184.1  microtubule-associated protein 10

      See identical proteins and their annotated locations for NP_083184.1

      Status: VALIDATED

      Source sequence(s)
      AI835009, AK080043, BB011955, BY073742
      Consensus CDS
      CCDS22780.1
      UniProtKB/Swiss-Prot
      Q5DTY2, Q8BJS7
      UniProtKB/TrEMBL
      Q9CUD6
      Related
      ENSMUSP00000061679.4, ENSMUST00000053078.5
      Conserved Domains (2) summary
      pfam14924
      Location:61142
      DUF4497; Protein of unknown function (DUF4497)
      pfam14925
      Location:243890
      HPHLAWLY; Domain of unknown function

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      126396557..126400104
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)