PRMT6 protein arginine methyltransferase 6 [Arabidopsis thaliana (thale cress)] - Gene

Summary

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Official Symbol: PRMT6
Official Full Name: protein arginine methyltransferase 6
Primary source: TAIR:AT3G20020
Locus tag: AT3G20020
See related: Araport:AT3G20020
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: ARABIDOPSIS THALIANA PROTEIN ARGININE METHYLTRANSFERASE 6; ATPRMT6; protein arginine methyltransferase 6
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Genomic context

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See PRMT6 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 13

Sequence:: Chromosome: 3; NC_003074.8 (6983702..6988101, complement)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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General gene information

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Homology

Orthologs from OrthoDB

NM_001084722.1

Supported by ESTs:

NM_001338447.1

Supported by ESTs:

NM_112893.4

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables protein-arginine N-methyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in regulation of photoperiodism, flowering	IGI Inferred from Genetic Interaction more info

Component	Evidence Code	Pubs
located_in cytoplasm	ISM Inferred from Sequence Model more info

General protein information

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Preferred Names: protein arginine methyltransferase 6

NP_001078191.1

protein arginine methyltransferase 6 (PRMT6); FUNCTIONS IN: protein methyltransferase activity, methyltransferase activity; INVOLVED IN: protein amino acid methylation; LOCATED IN: cytoplasm; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Ribosomal L11 methyltransferase, PrmA (InterPro:IPR010456); BEST Arabidopsis thaliana protein match is: protein arginine methyltransferase 1A (TAIR:AT2G19670.1); Has 2687 Blast hits to 2666 proteins in 709 species: Archae - 44; Bacteria - 791; Metazoa - 996; Fungi - 246; Plants - 285; Viruses - 0; Other Eukaryotes - 325 (source: NCBI BLink).

NP_188637.2

protein arginine methyltransferase 6 (PRMT6); FUNCTIONS IN: protein methyltransferase activity, methyltransferase activity; INVOLVED IN: protein amino acid methylation; LOCATED IN: cytoplasm; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 7 growth stages; CONTAINS InterPro DOMAIN/s: Ribosomal L11 methyltransferase, PrmA (InterPro:IPR010456); BEST Arabidopsis thaliana protein match is: protein arginine methyltransferase 1A (TAIR:AT2G19670.1); Has 5878 Blast hits to 5804 proteins in 1733 species: Archae - 156; Bacteria - 3349; Metazoa - 1214; Fungi - 260; Plants - 392; Viruses - 1; Other Eukaryotes - 506 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

6983702..6988101 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_112893.4 → NP_188637.2 protein arginine methyltransferase 6 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_188637.2

Status: REVIEWED

UniProtKB/Swiss-Prot

Q08A71, Q9LJZ9

UniProtKB/TrEMBL

A0A178V8Z6, A0A5S9XDU3, A0A654F8X2

Conserved Domains (3) summary

cd02440
Location:122 → 221

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

COG2520
Location:19 → 221

Trm5; tRNA G37 N-methylase Trm5 [Translation, ribosomal structure and biogenesis]

cl19115
Location:272 → 337

Cupredoxin; Cupredoxin superfamily
NM_001338447.1 → NP_001326463.1 protein arginine methyltransferase 6 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V8Z6, A0A178VA69, A0A1I9LPC6, A0A384KC56
NM_001084722.1 → NP_001078191.1 protein arginine methyltransferase 6 [Arabidopsis thaliana]

See identical proteins and their annotated locations for NP_001078191.1

Status: REVIEWED

UniProtKB/TrEMBL

A0A178V8Z6

Conserved Domains (4) summary

COG0500
Location:77 → 302

SmtA; SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only]

cl16912
Location:119 → 224

MDR; Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family

cl17173
Location:116 → 169

AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

cl19115
Location:250 → 315

Cupredoxin; Cupredoxin superfamily