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    ILL2 IAA-leucine resistant (ILR)-like 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 835767, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ILL2
    Official Full Name
    IAA-leucine resistant (ILR)-like 2
    Primary source
    TAIR:AT5G56660
    Locus tag
    AT5G56660
    See related
    Araport:AT5G56660
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    IAA-leucine resistant (ILR)-like 2; MIK19.11; MIK19_11
    Summary
    encodes IAA-amino acid hydrolase that has a broad range of substrate specificity. It is most active on IAA-Ala among the IAA-conjugate hydrolases tested.
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    Genomic context

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    See ILL2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (22933267..22935316)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene myo-inositol oxygenase 5 Neighboring gene IAA-leucine resistant (ILR)-like 1 Neighboring gene ncRNA Neighboring gene Ribosomal protein S30 family protein Neighboring gene Class II aminoacyl-tRNA and biotin synthetases superfamily protein Neighboring gene FBD, F-box and Leucine Rich Repeat domains containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. X-ray structure of ILL2, an auxin-conjugate amidohydrolase from Arabidopsis thaliana. Bitto E, et al. Proteins, 2009 Jan. PMID 18543330, Free PMC Article
    2. Characterization of a family of IAA-amino acid conjugate hydrolases from Arabidopsis. LeClere S, et al. J Biol Chem, 2002 Jun 7. PMID 11923288
    3. Putative glycosyltransferases and other plant Golgi apparatus proteins are revealed by LOPIT proteomics. Nikolovski N, et al. Plant Physiol, 2012 Oct. PMID 22923678, Free PMC Article
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    NM_125049.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables IAA-Ala conjugate hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables IAA-amino acid conjugate hydrolase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within auxin metabolic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in endoplasmic reticulum HDA PubMed 

    General protein information

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    Preferred Names
    IAA-leucine resistant (ILR)-like 2
    NP_200477.1
    • IAA-leucine resistant (ILR)-like 2 (ILL2); FUNCTIONS IN: metallopeptidase activity, IAA-amino acid conjugate hydrolase activity, IAA-Ala conjugate hydrolase activity; INVOLVED IN: proteolysis, auxin metabolic process; LOCATED IN: endomembrane system; CONTAINS InterPro DOMAIN/s: Peptidase M20 (InterPro:IPR002933), Peptidase M20D, amidohydrolase (InterPro:IPR010168), Peptidase M20D, mername-AA028/carboxypeptidase Ss1 (InterPro:IPR017439), Peptidase M20, dimerisation (InterPro:IPR011650); BEST Arabidopsis thaliana protein match is: IAA-leucine resistant (ILR)-like 1 (TAIR:AT5G56650.1); Has 12923 Blast hits to 12915 proteins in 1981 species: Archae - 133; Bacteria - 9506; Metazoa - 56; Fungi - 252; Plants - 310; Viruses - 0; Other Eukaryotes - 2666 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      22933267..22935316
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_125049.3 → NP_200477.1  IAA-leucine resistant (ILR)-like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_200477.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O49221, P54970
      UniProtKB/TrEMBL
      A0A654GBR6, Q5HZ30
      Conserved Domains (1) summary
      PLN02693
      Location:25 → 439
      PLN02693; IAA-amino acid hydrolase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P54970.2

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