efhb EF-hand domain family, member B [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: efhbprovided by ZNC
Official Full Name: EF-hand domain family, member Bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-091001-1
See related: Ensembl:ENSDARG00000069703 AllianceGenome:ZFIN:ZDB-GENE-091001-1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable calcium ion binding activity. Orthologous to human EFHB (EF-hand domain family member B). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 13

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (49629886..49646625, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (49405893..49422632, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: EF-hand domain-containing family member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001201489.1 → NP_001188418.1 EF-hand domain-containing family member B

Status: VALIDATED

Source sequence(s)

BM025880, BM026114, EB917642, EB968468, EE316624

UniProtKB/TrEMBL

A0A8M1NYK5, E7F7T9

Related

ENSDARP00000092403.3, ENSDART00000101629.5

Conserved Domains (2) summary

cd00051
Location:325 → 381

EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...

pfam13499
Location:325 → 385

EF-hand_7; EF-hand domain pair