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    tmem254 transmembrane protein 254 [ Danio rerio (zebrafish) ]

    Gene ID: 393341, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tmem254provided by ZNC
    Official Full Name
    transmembrane protein 254provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1348
    See related
    Ensembl:ENSDARG00000109902 AllianceGenome:ZFIN:ZDB-GENE-040426-1348
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:64043
    Summary
    Predicted to be located in membrane. Is expressed in central nervous system; cranial ganglion; and trigeminal placode. Orthologous to human TMEM254 (transmembrane protein 254). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    human mouse all
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    Genomic context

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    See tmem254 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (52080589..52089140, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (51735363..51743451, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene inositol polyphosphate-5-phosphatase A Neighboring gene kinesin light chain 1b Neighboring gene transmembrane protein 121 Neighboring gene uncharacterized LOC100331665 Neighboring gene L-threonine ammonia-lyase-like Neighboring gene serine/threonine-protein kinase 32C Neighboring gene uncharacterized LOC100535731

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Microarray analysis of zebrafish cloche mutant using amplified cDNA and identification of potential downstream target genes. Qian F, et al. Dev Dyn, 2005 Jul. PMID 15937927
    2. Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification. Reischauer S, et al. Nature, 2016 Jul 14. PMID 27411634
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC64043

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 254

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200370.2 → NP_956664.2  transmembrane protein 254

      Status: VALIDATED

      Source sequence(s)
      CABZ01089780
      UniProtKB/TrEMBL
      Q7T380
      Related
      ENSDARP00000151499.1, ENSDART00000187600.1
      Conserved Domains (1) summary
      pfam14934
      Location:27 → 112
      DUF4499; Domain of unknown function (DUF4499)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      52080589..52089140 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068224944.1 → XP_068081045.1  transmembrane protein 254 isoform X1

      UniProtKB/TrEMBL
      Q7T380
    Nucleotide Protein Strain
    Heading Accession and Version

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