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    SYN2 Rad21/Rec8-like family protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 834084, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SYN2
    Official Full Name
    Rad21/Rec8-like family protein
    Primary source
    TAIR:AT5G40840
    Locus tag
    AT5G40840
    See related
    Araport:AT5G40840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtRAD21.1; MHK7.7; MHK7_7; Sister chromatid cohesion 1 (SCC1) protein homolog 2
    Summary
    Cohesion family protein SYN2 (SYN2).
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    Genomic context

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    See SYN2 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    13
    Sequence:
    Chromosome: 5; NC_003076.8 (16359331..16363878, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene Cytochrome C1 family Neighboring gene Ataxia telangiectasia-mutated and RAD3-like protein Neighboring gene S-adenosyl-L-methionine-dependent methyltransferases superfamily protein Neighboring gene urophorphyrin methylase 1 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The AtRAD21.1 and AtRAD21.3 Arabidopsis cohesins play a synergistic role in somatic DNA double strand break damage repair. da Costa-Nunes JA, et al. BMC Plant Biol, 2014 Dec 16. PMID 25511710, Free PMC Article
    2. Cloning and characterization of two Arabidopsis genes that belong to the RAD21/REC8 family of chromosome cohesin proteins. Dong F, et al. Gene, 2001 Jun 13. PMID 11410371
    3. Rapid repair of DNA double strand breaks in Arabidopsis thaliana is dependent on proteins involved in chromosome structure maintenance. Kozak J, et al. DNA Repair (Amst), 2009 Mar 1. PMID 19070688
    4. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    General gene information

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    NM_001125872.1
    NM_001344360.1
    NM_001344361.1
    NM_001344362.1
    NM_123449.3
    NM_180779.2

    Gene Ontology Provided by TAIR

    Process Evidence Code Pubs
    acts_upstream_of_or_within double-strand break repair IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within mitotic cell cycle IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    involved_in sister chromatid cohesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cohesin complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Rad21/Rec8-like family protein
    NP_001119344.1
    • SYN2; CONTAINS InterPro DOMAIN/s: Rad21/Rec8 like protein, C-terminal (InterPro:IPR006909); BEST Arabidopsis thaliana protein match is: sister chromatid cohesion 1 protein 4 (TAIR:AT5G16270.1); Has 30201 Blast hits to 17322 proteins in 780 species: Archae - 12; Bacteria - 1396; Metazoa - 17338; Fungi - 3422; Plants - 5037; Viruses - 0; Other Eukaryotes - 2996 (source: NCBI BLink).
    NP_568586.2
    • SYN2; CONTAINS InterPro DOMAIN/s: Rad21/Rec8 like protein, C-terminal (InterPro:IPR006909), Rad21/Rec8 like protein, N-terminal (InterPro:IPR006910); BEST Arabidopsis thaliana protein match is: sister chromatid cohesion 1 protein 4 (TAIR:AT5G16270.1); Has 1194 Blast hits to 931 proteins in 243 species: Archae - 0; Bacteria - 76; Metazoa - 473; Fungi - 219; Plants - 243; Viruses - 3; Other Eukaryotes - 180 (source: NCBI BLink).
    NP_851110.1
    • SYN2; CONTAINS InterPro DOMAIN/s: Rad21/Rec8 like protein, C-terminal (InterPro:IPR006909), Rad21/Rec8 like protein, N-terminal (InterPro:IPR006910); BEST Arabidopsis thaliana protein match is: sister chromatid cohesion 1 protein 4 (TAIR:AT5G16270.1); Has 1217 Blast hits to 955 proteins in 245 species: Archae - 0; Bacteria - 80; Metazoa - 480; Fungi - 224; Plants - 240; Viruses - 3; Other Eukaryotes - 190 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      16359331..16363878 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180779.2 → NP_851110.1  Rad21/Rec8-like family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851110.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654G6P7
      Conserved Domains (2) summary
      pfam04824
      Location:755 → 805
      Rad21_Rec8; Conserved region of Rad21 / Rec8 like protein
      pfam04825
      Location:1 → 87
      Rad21_Rec8_N; N terminus of Rad21 / Rec8 like protein

    2. NM_123449.3 → NP_568586.2  Rad21/Rec8-like family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568586.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8W1Y1, Q8W1Y2, Q9FKS2, Q9FQ20
      UniProtKB/TrEMBL
      A0A654G6P7, A0A7G2FJJ3
      Conserved Domains (2) summary
      pfam04824
      Location:756 → 806
      Rad21_Rec8; Conserved region of Rad21 / Rec8 like protein
      pfam04825
      Location:1 → 87
      Rad21_Rec8_N; N terminus of Rad21 / Rec8 like protein

    3. NM_001344360.1 → NP_001330091.1  Rad21/Rec8-like family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B9P6, A0A654G6P7

    4. NM_001344362.1 → NP_001330093.1  Rad21/Rec8-like family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B9R6

    5. NM_001125872.1 → NP_001119344.1  Rad21/Rec8-like family protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001119344.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3H605
      Conserved Domains (1) summary
      pfam04824
      Location:624 → 674
      Rad21_Rec8; Conserved region of Rad21 / Rec8 like protein

    6. NM_001344361.1 → NP_001330092.1  Rad21/Rec8-like family protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8B9R2, A0A654G6P7
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9FQ20.2

    Gene LinkOut

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