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    GLX2-4 glyoxalase 2-4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837122, updated on 18-Sep-2024

    Summary

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    Official Symbol
    GLX2-4
    Official Full Name
    glyoxalase 2-4
    Primary source
    TAIR:AT1G06130
    Locus tag
    AT1G06130
    See related
    Araport:AT1G06130
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    glyoxalase 2-4; T21E18.18; T21E18_18
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    Genomic context

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    See GLX2-4 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    8
    Sequence:
    Chromosome: 1; NC_003070.9 (1857757..1860938, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene SKP1/ASK-interacting protein 16 Neighboring gene Fatty acid desaturase family protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    2. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    3. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_100494.5
    NM_179268.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables hydroxyacylglutathione hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    glyoxalase 2-4
    NP_563760.1
    • glyoxalase 2-4 (GLX2-4); FUNCTIONS IN: hydrolase activity, zinc ion binding, hydroxyacylglutathione hydrolase activity; INVOLVED IN: methylglyoxal catabolic process to D-lactate; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Beta-lactamase-like (InterPro:IPR001279), Hydroxyacylglutathione hydrolase (InterPro:IPR017782); BEST Arabidopsis thaliana protein match is: glyoxalase 2-5 (TAIR:AT2G31350.1); Has 15456 Blast hits to 15455 proteins in 2500 species: Archae - 395; Bacteria - 9969; Metazoa - 478; Fungi - 329; Plants - 213; Viruses - 0; Other Eukaryotes - 4072 (source: NCBI BLink).
    NP_849599.1
    • glyoxalase 2-4 (GLX2-4); FUNCTIONS IN: hydrolase activity, hydroxyacylglutathione hydrolase activity, zinc ion binding; INVOLVED IN: methylglyoxal catabolic process to D-lactate; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Beta-lactamase-like (InterPro:IPR001279), Hydroxyacylglutathione hydrolase (InterPro:IPR017782); BEST Arabidopsis thaliana protein match is: glyoxalase 2-5 (TAIR:AT2G31350.2); Has 15453 Blast hits to 15452 proteins in 2500 species: Archae - 395; Bacteria - 9967; Metazoa - 477; Fungi - 329; Plants - 213; Viruses - 0; Other Eukaryotes - 4072 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1857757..1860938 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100494.5 → NP_563760.1  glyoxalase 2-4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_563760.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L451, Q8LDW8, Q9LND5
      UniProtKB/TrEMBL
      A0A178WGQ2, A0A5S9SWM4, A0A7G2DS75
      Conserved Domains (1) summary
      PLN02398
      Location:1 → 329
      PLN02398; hydroxyacylglutathione hydrolase

    2. NM_179268.2 → NP_849599.1  glyoxalase 2-4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_849599.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2DS75
      Conserved Domains (3) summary
      PLN02398
      Location:1 → 328
      PLN02398; hydroxyacylglutathione hydrolase
      pfam16123
      Location:244 → 327
      HAGH_C; Hydroxyacylglutathione hydrolase C-terminus
      cd07723
      Location:80 → 243
      hydroxyacylglutathione_hydrolase_MBL-fold; hydroxyacylglutathione hydrolase, MBL-fold metallo-hydrolase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8LDW8.1

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