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    Tmem117 transmembrane protein 117 [ Mus musculus (house mouse) ]

    Gene ID: 320709, updated on 27-Nov-2024

    Summary

    Official Symbol
    Tmem117provided by MGI
    Official Full Name
    transmembrane protein 117provided by MGI
    Primary source
    MGI:MGI:2444580
    See related
    Ensembl:ENSMUSG00000063296 AllianceGenome:MGI:2444580
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B930062P21Rik
    Summary
    Predicted to be involved in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum and plasma membrane. Orthologous to human TMEM117 (transmembrane protein 117). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in large intestine adult (RPKM 7.6), cerebellum adult (RPKM 2.2) and 14 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tmem117 in Genome Data Viewer
    Location:
    15 E3; 15 48.65 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (94527066..94993978)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (94629185..95096097)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_39550 Neighboring gene STARR-positive B cell enhancer ABC_E7408 Neighboring gene STARR-seq mESC enhancer starr_39553 Neighboring gene predicted gene, 30754 Neighboring gene twinfilin actin binding protein 1 Neighboring gene STARR-seq mESC enhancer starr_39558 Neighboring gene STARR-seq mESC enhancer starr_39559 Neighboring gene predicted gene, 25546 Neighboring gene STARR-seq mESC enhancer starr_39560 Neighboring gene predicted gene, 31007 Neighboring gene STARR-seq mESC enhancer starr_39561 Neighboring gene predicted gene, 23129 Neighboring gene predicted gene, 52203 Neighboring gene predicted gene, 30953 Neighboring gene uncharacterized LOC100043315 Neighboring gene predicted gene, 30810 Neighboring gene STARR-seq mESC enhancer starr_39563 Neighboring gene predicted gene, 31075

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2)  1 citation
    • Gene trapped (1) 
    • Targeted (1)  1 citation
    • Transposon induced (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178789.4NP_848904.1  transmembrane protein 117

      See identical proteins and their annotated locations for NP_848904.1

      Status: PROVISIONAL

      Source sequence(s)
      AC102905, AC118683, AC147160, AC158918
      Consensus CDS
      CCDS27774.1
      UniProtKB/Swiss-Prot
      Q8BH18, Q8C6X8
      Related
      ENSMUSP00000079038.5, ENSMUST00000080141.6
      Conserved Domains (1) summary
      pfam15113
      Location:4403
      TMEM117; TMEM117 protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      94527066..94993978
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)